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Bull Exp Biol Med ; 172(1): 38-41, 2021 Nov.
Article in English | MEDLINE | ID: mdl-34792717

ABSTRACT

Elucidation of the pharmacodynamic mechanisms of drugs capable of potentiating the effects of non-steroidal anti-inflammatory drugs is an important task. In this in vitro study, the ability of Traumeel S to influence the innate and acquired immunity was evaluated. Traumeel S was found to reduce activities of NADPH oxidase and neutrophil extracellular traps, as well as to evoke anti-inflammatory activity of lymphocyte subpopulations.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Anti-Inflammatory Agents/pharmacology , Extracellular Traps/immunology , Minerals/pharmacology , NADPH Oxidases/metabolism , Plant Extracts/pharmacology , Adaptive Immunity/drug effects , HLA-DR Antigens/immunology , Humans , Immunity, Innate/drug effects , Inflammation/drug therapy , Inflammation/pathology , Leukocytosis/immunology , Lymphocyte Subsets/immunology , Neutrophils/immunology , T-Lymphocytes/immunology , fas Receptor/analysis
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