ABSTRACT
Eighty-two outpatients who received general anaesthesia for surgical removal of maxillary or mandibular third molars were given either diclofenac 75 mg or nefopam 20 mg intramuscularly for postoperative pain control. They and the control group were also allowed oral paracetamol as required. The results showed that there was no significant pain relief from these single intramuscular injections.
Subject(s)
Diclofenac/therapeutic use , Nefopam/therapeutic use , Oxazocines/therapeutic use , Pain, Postoperative/drug therapy , Tooth Extraction , Adult , Ambulatory Surgical Procedures , Anesthesia, Dental , Anesthesia, General , Double-Blind Method , Female , Humans , Male , Randomized Controlled Trials as TopicABSTRACT
A prolonged electrocardiographic QT interval may be harmful during general anaesthesia. It may be prudent, therefore, to select anaesthetic agents which have the least effect on the QT interval. In a controlled study, propofol has been shown to have less effect on the QT interval than thiopentone (P less than 0.05). Our data suggest also that any effects which may be caused by enflurane and isoflurane are masked by the effects of the induction agent.
Subject(s)
Anesthesia, Inhalation , Anesthesia, Intravenous , Heart/drug effects , Propofol/pharmacology , Thiopental/pharmacology , Anesthesia, General , Electrocardiography/drug effects , Female , Humans , Time FactorsABSTRACT
Twenty patients, ASA grades 1 and 2, aged 18-65 years were admitted to an open study to investigate the ease of tracheal intubation after induction of anaesthesia with propofol without the use of muscle relaxants after the chance observation that propofol 2.5 mg/kg allowed easy laryngoscopy and tracheal intubation. Satisfactory intubation conditions were achieved in 19 patients.
