Septuagenarians Approach 4 Times the Basal Metabolic Rate During Race Across America.

BACKGROUND: Previous data have demonstrated that Tour de France riders maintain total daily energy expenditure (TDEE) between 3.5 and 5.5 times the basal metabolic rate (×BMR). In contrast, TDEE for healthy male septuagenarians has been reported to average 1.3 to 2.0 ×BMR. PURPOSE: Measure the TDEE and water efflux during ultraendurance work in an older population during the cross-continent cycling Race Across America. METHODS: A 4-man septuagenarian team (70 [1.6] y, 72.0 [5.1] kg) received an oral dose of doubly labeled water prior to completing the Race Across America (4817 km, 51,816 m of climbing) for TDEE calculation. Nude body weight measures were coupled with collected urine samples. RESULTS: The race was completed in approximately 6.5 days (official time: 6 d, 13 h, and 13 min) with an average speed of 30.6 (0.7) km·h-1 (age-group course record). Body weight remained unchanged (prerace: 70.4 [5.8] kg, postrace: 70.0 [5.3] kg). TDEE was calculated over 3 race segments. TDEE varied between individual riders and segments throughout the continuous event (24.7 [4.2] MJ·24 h-1, 5900 [1015] kcals·24 h-1, 3.4 [0.5] ×BMR). Water efflux averaged 10.2 (0.8) L·24 h-1 resulting in a total turnover of 45.3 (3.9) L amounting to 1.5 (0.2) times initial total body water during the race. CONCLUSIONS: Highly active septuagenarians maintain body weight prerace to postrace, suggesting near energy balance when TDEE approaches 4 ×BMR. These values exceed twice those of previously observed healthy but less active septuagenarian men and are comparable to professional riders during portions of the Tour de France. Advanced age and high metabolic output are not mutually exclusive.

Effects of commercially available pneumatic compression on muscle glycogen recovery after exercise.

The purpose of this study was to investigate the effects of pneumatic compression pants on postexercise glycogen resynthesis. Active male subjects (n = 10) completed 2 trials consisting of a 90-minute glycogen depleting ride, followed by 4 hours of recovery with either a pneumatic compression device (PCD) or passive recovery (PR) in a random counterbalanced order. A carbohydrate beverage (1.8 g·kg bodyweight) was provided at 0 and 2 hours after exercise. Muscle biopsies (vastus lateralis) were obtained immediately and 4 hours after exercise for glycogen analyses. Blood samples were collected throughout recovery to measure glucose and insulin. Eight fingerstick blood samples for lactate were collected in the last 20 minutes of the exercise period and during the initial portion of the recovery period. Heart rate was monitored throughout the trial. During the PCD trial, subjects recovered using a commercially available recovery device (NormaTec PCD) operational at 0-60 and 120-180 minutes into recovery period. The same PCD was worn during the PR trial but was not turned on to create pulsatile pressures. There was no difference in muscle glycogen resynthesis during the recovery period (6.9 ± 0.8 and 6.9 ± 0.5 mmol·kg wet wt·h for the PR and PCD trials, respectively). Blood glucose, insulin, and lactate concentrations changed with respect to time but were not different between trials (p > 0.05). The use of PCD did not alter the rate of muscle glycogen resynthesis, blood lactate, or blood glucose and insulin concentrations associated with a postexercise oral glucose load.

Patients with type 1 diabetes oxidize fat at a greater rate than age- and sex-matched controls.

INTRODUCTION: Elevated patient blood glucose and exogenous insulin administration may affect substrate oxidation in patients with type 1 diabetes mellitus (T1DM); however, this has not been demonstrated with conviction. We examined substrate oxidation during incremental exercise in a group of subjects with T1DM and compared the results to those of an age- and sex-matched control group of subjects. METHODS: A group of subjects with T1DM (n = 29; 10 men, 19 women) was recruited for metabolic testing from a weeklong fitness camp. An age- and sex-matched control group of subjects (n = 29; 10 men, 19 women) was recruited from the local community. Subjects were required to avoid strenuous exercise for 48 hours and fast for 2 hours prior to metabolic testing. An incremental test to exhaustion on either a stationary cycle or treadmill was administered to all subjects. Maximum oxygen consumption of subjects was measured (T1DM subjects: 41.4 ± 1.9 mL/kg/min; control subjects: 48.4 ± 1.3 mL/kg/min). Blood glucose was recorded at 20 and 5 minutes before the exercise test, and at 5 and 20 minutes after the exercise test. RESULTS: The T1DM and control subjects were matched for age, height, weight, and body composition. Subject blood glucose levels were higher in the group of subjects with T1DM than the control group at all times measured (P < 0.001). At all relative intensities of exercise (50%-80% maximum oxygen consumption; P < 0.050), absolute fat oxidation was higher in the group of subjects with T1DM (P < 0.050) and absolute carbohydrate oxidation was higher in the control group. CONCLUSION: Our data indicate that subjects with T1DM oxidize fat at a higher rate and carbohydrates at a lower rate when compared with age- and sex-matched controls at the same relative intensity of exercise, despite the elevated pre-exercise blood glucose of subjects with T1DM.