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1.
Paediatr Drugs ; 11(3): 171-83, 2009.
Article in English | MEDLINE | ID: mdl-19445546

ABSTRACT

Pediatric generalized anxiety disorder (GAD) is characterized by excessive and uncontrollable worry about a variety of events and is accompanied by physical symptoms such as headaches, tension, restlessness, gastrointestinal distress, and heart palpitations. Symptoms impose marked distress and interfere with social, emotional, and educational functioning. GAD occurs in over 10% of children and adolescents, has an average age of onset of 8.5 years, and is more often reported in girls. Common co-occurring conditions include separation anxiety disorder and social phobia. Assessment involves a multi-informant, multi-method approach involving the child, parents, and school teachers. A clinical interview should be conducted to assess for the three primary ways anxiety presents: behaviors, thoughts, and somatic symptoms. Several semi-structured diagnostic interviews are available, and the Anxiety Disorders Interview Schedule is increasingly used. Rating scales completed by the patient, caregivers, and teachers provide useful information for diagnosis and symptom monitoring. Several scales are available to assess patients for the Diagnostic and Statistical Manual of Mental Disorders (4th Edition) GAD diagnosis; however, instruments generally cannot distinguish children with GAD from children with similar anxiety disorders. Both cognitive-behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) have demonstrated efficacy for the treatment of pediatric anxiety disorders including GAD. Evidence suggests that the combination of CBT plus sertraline offers additional benefit compared with either treatment alone. With pharmacotherapy, systematic tracking of treatment-emergent adverse events such as headaches, stomach aches, behavioral activation, worsening symptoms, and emerging suicidal thoughts is important. Recommended starting doses are fluvoxamine 25 mg/day, fluoxetine 10 mg/day, and sertraline 25 mg/day, though lower starting doses are possible. Dosing can be adjusted as often as weekly with the goal of achieving a high-quality response, while minimizing side effects. Long-term treatment with medication has not been well studied; however, to achieve optimal long-term outcome extended use of medication may be required. It is recommended to continue medication for approximately 1 year following remission in symptoms, and when discontinuing medication to choose a stress-free time of the year. If symptoms return, medication re-initiation should be considered seriously.


Subject(s)
Anxiety Disorders , Cognitive Behavioral Therapy , Selective Serotonin Reuptake Inhibitors/therapeutic use , Adolescent , Anxiety Disorders/diagnosis , Anxiety Disorders/epidemiology , Anxiety Disorders/therapy , Child , Drug Administration Schedule , Humans , Psychiatric Status Rating Scales , Selective Serotonin Reuptake Inhibitors/administration & dosage
2.
J Fam Psychol ; 22(2): 212-21, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18410208

ABSTRACT

In this study, the authors examined the relationship between sense of control and depressive and anxious symptoms for mothers and fathers during the 1st year of parenthood. Participants were 153 dual-earner, working-class couples who were recruited during the 3rd trimester of pregnancy at prenatal education courses. Data were collected 1 month antenatally and 1, 4, 6, and 12 months postnatally. Sense of control was decomposed into 2 distinct parts: an enduring component and a malleable component that changes with context. Consistent with a cognitive theory of emotional problems, results demonstrated that a sense of control served a protective function for mental health outcomes. A higher sense of enduring control predicted lower levels of psychological distress for new parents, and increases in control over time predicted decreases in depression and anxiety. Findings hold implications for interventions with expectant parents, such as expanding prenatal education courses to include strategies for enhancing and maintaining a sense of personal control.


Subject(s)
Adaptation, Psychological , Anxiety Disorders/psychology , Depressive Disorder/psychology , Internal-External Control , Parents/psychology , Perception , Adult , Anxiety Disorders/diagnosis , Anxiety Disorders/etiology , Depressive Disorder/diagnosis , Depressive Disorder/etiology , Female , Follow-Up Studies , Humans , Life Change Events , Male , Predictive Value of Tests , Pregnancy , Regression Analysis , Stress, Psychological/diagnosis , Stress, Psychological/etiology , Stress, Psychological/psychology
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