ABSTRACT
A protective mucous barrier of the stomach was studied in 153 patients with duodenal ulcer disease. Before the operation in 70 patients, decrease in concentration of protective factors of gastric mucus, especially in complicated form of ulcer disease was noted. More complete restoration of a protective barrier was noted after organ-preserving operations with excision of ulcerous substrate (in 54 patients) than after those without its excision (in 29).
Subject(s)
Duodenal Ulcer/physiopathology , Gastric Mucins/metabolism , Gastric Mucosa/metabolism , Vagotomy, Proximal Gastric , Adolescent , Adult , Aged , Duodenal Ulcer/surgery , Female , Fucose/chemistry , Gastric Mucins/chemistry , Hexosamines/chemistry , Humans , Male , Middle Aged , Postoperative Period , Sialic Acids/chemistryABSTRACT
The authors treated 106 patients with retroampullary duodenal ulcer. Resections were performed in 16, the organ-preserving operations--in 89 patients. In 58 (64.8%) cases, the duodenoplasty with the different types of vagotomy and preservation of the pyloric sphincter using the techniques developed in the clinic was performed.