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Heart ; 104(17): 1417-1423, 2018 09.
Article in English | MEDLINE | ID: mdl-29472291

ABSTRACT

OBJECTIVE: Surgical coronary revascularisation in children with congenital heart disease (CHD) is a rare event for which limited information is available. In this study, we review the indications and outcomes of surgical coronary revascularisation from the Pediatric Cardiac Care Consortium, a large US-based multicentre registry of interventions for CHD. METHODS: This is a retrospective cohort study of children (<18 years old) with CHD who underwent surgical coronary revascularisation between 1982 and 2011. In-hospital mortality and graft patency data were obtained from the registry. Long-term transplant-free survival through 2014 was achieved for patients with adequate identifiers via linkage with the US National Death Index and the Organ Procurement and Transplantation Network. RESULTS: Coronary revascularisation was accomplished by bypass grafting (n=72, median age 6.8 years, range 3 days-17.4 years) or other operations (n=65, median age 2.6 years, range 5 days-16.7 years) in 137 patients. Most revascularisations were related to the aortic root (61.3%) or coronary anomalies (27.7%), but 10.9% of them were unrelated to either of them. Twenty in-hospital deaths occurred, 70% of them after urgent 'rescue' revascularisation in association with another operation. Long-term outcomes were available by external linkage for 54 patients surviving to hospital discharge (median follow-up time 15.0 years, max follow-up 29.8 years) with a 15-year transplant-free survival of 91% (95% CI 83% to 99%). CONCLUSIONS: Surgical coronary revascularisation can be performed in children with CHD with acceptable immediate and long-term survival. Outcomes are dependent on indication, with the highest mortality in rescue procedures.


Subject(s)
Heart Defects, Congenital/surgery , Long Term Adverse Effects , Myocardial Revascularization , Adolescent , Child, Preschool , Female , Follow-Up Studies , Heart Defects, Congenital/epidemiology , Hospital Mortality , Humans , Infant, Newborn , Long Term Adverse Effects/epidemiology , Long Term Adverse Effects/etiology , Male , Myocardial Revascularization/adverse effects , Myocardial Revascularization/classification , Myocardial Revascularization/methods , Myocardial Revascularization/mortality , Outcome and Process Assessment, Health Care , Registries/statistics & numerical data , Retrospective Studies , Survival Analysis , United States/epidemiology
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