Open(G)PIAS: An Open-Source Solution for the Construction of a High-Precision Acoustic Startle Response Setup for Tinnitus Screening and Threshold Estimation in Rodents.

The modulation of the acoustic startle reflex (ASR) by a pre-stimulus called pre-pulse inhibition (PPI, for gap of silence pre-stimulus: GPIAS) is a versatile tool to, e.g., estimate hearing thresholds or identify subjective tinnitus percepts in rodents. A proper application of these paradigms depends on a reliable measurement of the ASR amplitudes and an exact stimulus presentation in terms of frequency and intensity. Here, we introduce a novel open-source solution for the construction of a low-cost ASR setup. The complete software for data acquisition and stimulus presentation is written in Python 3.6 and is provided as an Anaconda package. Furthermore, we provide a construction plan for the sensor system based on low-cost hardware components. Exemplary GPIAS data from two animal models (Mus musculus, Meriones unguiculatus) show that the ratio histograms (1-GPIAS) of the gap-pre-stimulus and no pre-stimulus ASR amplitudes can be well described by a log-normal distribution being in good accordance to previous studies with already established setups. Furthermore, it can be shown that the PPI as a function of pre-stimulus intensity (threshold paradigm) can be approximated with a hard-sigmoid function enabling a reproducible sensory threshold estimation. Thus, we show that the open-source solution could help to further establish the ASR method in many laboratories and, thus, facilitate and standardize research in animal models of tinnitus and/or hearing loss.

Acoustic reciprocity: An extension to spherical harmonics domain.

Acoustic reciprocity is a fundamental property of acoustic wavefields that is commonly used to simplify the measurement process of many practical applications. Traditionally, the reciprocity theorem is defined between a monopole point source and a point receiver. Intuitively, it must apply to more complex transducers than monopoles. In this paper, the authors formulate the acoustic reciprocity theory in the spherical harmonics domain for directional sources and directional receivers with higher order directivity patterns.

A model for the temporal evolution of the spatial coherence in decaying reverberant sound fields.

Reverberant sound fields are often modeled as isotropic. However, it has been observed that spatial properties change during the decay of the sound field energy, due to non-isotropic attenuation in non-ideal rooms. In this letter, a model for the spatial coherence between two sensors in a decaying reverberant sound field is developed for rectangular rooms. The modeled coherence function depends on room dimensions, surface reflectivity, and orientation of the sensor pair, but is independent of the position of source and sensors in the room. The model includes the spherically isotropic (diffuse) and cylindrically isotropic sound field models as special cases.

Room geometry inference based on spherical microphone array eigenbeam processing.

The knowledge of parameters characterizing an acoustic environment, such as the geometric information about a room, can be used to enhance the performance of several audio applications. In this paper, a novel method for three-dimensional room geometry inference based on robust and high-resolution beamforming techniques for spherical microphone arrays is presented. Unlike other approaches that are based on the measurement and processing of multiple room impulse responses, here, microphone array signal processing techniques for uncontrolled broadband acoustic signals are applied. First, the directions of arrival (DOAs) and time differences of arrival (TDOAs) of the direct signal and room reflections are estimated using high-resolution robust broadband beamforming techniques and cross-correlation analysis. In this context, the main challenges include the low reflected-signal to background-noise power ratio, the low energy of reflected signals relative to the direct signal, and their strong correlation with the direct signal and among each other. Second, the DOA and TDOA information is combined to infer the room geometry using geometric relations. The high accuracy of the proposed room geometry inference technique is confirmed by experimental evaluations based on both simulated and measured data for moderately reverberant rooms.

Localization of distinct reflections in rooms using spherical microphone array eigenbeam processing.

This paper presents an experimental and comparative study of several spherical microphone array eigenbeam (EB) processing techniques for localization of early reflections in room acoustic environments, which is a relevant research topic in both audio signal processing and room acoustics. This paper focuses on steered beamformer-based and subspace-based localization techniques implemented in the spherical EB domain, including the plane-wave decomposition, eigenbeam delay and sum, eigenbeam minimum variance distortionless response, eigenbeam multiple signal classification (EB-MUSIC), and eigenbeam estimation of signal parameters via rotational invariance techniques (EB-ESPRIT) methods. The directions of arrival of the original sound source and the associated reflection signals in acoustic environments are estimated from acoustic maps of the rooms, which are obtained using a spherical microphone array. The EB-domain-based frequency smoothing and white noise gain control techniques are derived and employed to improve the performance and robustness of reflection localization. The applicability of the presented methods in practice is confirmed by experiments carried out in real rooms.