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J Pediatr Hematol Oncol ; 39(2): 133-136, 2017 03.
Article in English | MEDLINE | ID: mdl-28060123

ABSTRACT

BACKGROUND: We report the use of diffusion-weighted imaging with background suppression (DWIBS) in pediatric virtual magnetic resonance imaging (MRI) autopsy of a child who succumbed to chordoma. CASE DESCRIPTION: A 10-year-old girl who succumbed to relapse of a chordoma underwent whole-body virtual MRI autopsy 12 hours postmortem with short Tau inversion recovery (STIR) and DWIBS on 3 T, which demonstrated the primary mass, local and cardiac invasion, and metastatic disease to the thorax, abdomen, head/neck, and musculoskeletal system. CONCLUSIONS: Postmortem virtual MRI autopsy including DWIBS successfully demonstrated the transthoracic spread of chordoma and invasion of the heart, resulting in blood-borne metastases. Motion and respiratory artifact were not factors during virtual autopsy using DWIBS on 3 T, making ideal use of this technology.


Subject(s)
Autopsy/methods , Chordoma/diagnostic imaging , Magnetic Resonance Imaging/methods , Thoracic Neoplasms/diagnostic imaging , User-Computer Interface , Abdominal Neoplasms/diagnostic imaging , Abdominal Neoplasms/secondary , Autopsy/instrumentation , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/secondary , Child , Chordoma/pathology , Female , Head and Neck Neoplasms/diagnostic imaging , Head and Neck Neoplasms/secondary , Heart/diagnostic imaging , Humans , Magnetic Resonance Imaging/instrumentation , Myocardium/pathology , Neoplasm Invasiveness , Neoplasm Metastasis , Thoracic Neoplasms/pathology
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