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1.
Chlorhexidine Inefficacy in Ventilated Patients: Comment.
Kempen, Paul Martin.
Anesthesiology ; 131(4): 938-939, 2019 10.
Article in English | MEDLINE | ID: mdl-31403498

Subject(s)
Anti-Infective Agents, Local , Pneumonia, Ventilator-Associated , Chlorhexidine , Humans
2.
Essential Thrombocytosis and Labor Epidural Placement While on Aspirin: Assessing Hemorrhagic Risks: A Case Report.
Kempen, Paul Martin.
A A Case Rep ; 9(6): 172-174, 2017 Sep 15.
Article in English | MEDLINE | ID: mdl-28520566

ABSTRACT

Essential thrombocytosis (ET) is a rare disease with known thrombotic and bleeding complications. We encountered a patient with a diagnosis of longstanding Janus kinase-2 gene-negative ET on aspirin therapy presenting for labor epidural. Evaluation of platelet function with point-of-care analysis using Plateletworks in a community hospital setting allowed confirmation of adequate numbers of functional platelets to support safe epidural placement. The relevant issues of ET for anesthesia management with labor epidurals are discussed. Unique, relevant, and unexpected findings from the platelet function testing are presented.


Subject(s)
Anesthesia, Epidural/methods , Labor, Obstetric , Thrombocythemia, Essential/complications , Adult , Aspirin/therapeutic use , Bupivacaine/administration & dosage , Female , Fentanyl/administration & dosage , Humans , Lidocaine/administration & dosage , Pregnancy
3.
The War on Drugs...or Doctors?
Kempen, Paul Martin.
W V Med J ; 113(2): 24-5, 2017.
Article in English | MEDLINE | ID: mdl-29373006

Subject(s)
Drug Monitoring/statistics & numerical data , Drug Prescriptions/standards , Legislation, Drug , Physicians/standards , Practice Patterns, Physicians'/standards , Attitude of Health Personnel , Humans , Pharmaceutical Preparations , United States
4.
THE METAMORPHOSIS OF MEDICINE. Opportunities for Physician Leadership NOW!
Kempen, Paul Martin.
W V Med J ; 112(2): 8-9, 2016.
Article in English | MEDLINE | ID: mdl-27025110

Subject(s)
Delivery of Health Care/economics , Insurance, Health/economics , Leadership , Politics , Delivery of Health Care/trends , Humans , Insurance, Health/trends , Managed Care Programs/economics , Medical Records Systems, Computerized/economics , Medicine/trends , Metaphor , Patient Protection and Affordable Care Act/economics , Physician Executives/trends , Physician-Patient Relations , Robotic Surgical Procedures/economics , West Virginia
5.
Rationally addressing the opiate drug problem.
Kempen, Paul Martin.
W V Med J ; 112(6): 8, 2016.
Article in English | MEDLINE | ID: mdl-29368495

Subject(s)
Analgesics, Opioid/adverse effects , Drug Prescriptions/statistics & numerical data , Family Practice , Opioid-Related Disorders/epidemiology , Pain/drug therapy , Analgesics, Opioid/administration & dosage , Humans , Opioid-Related Disorders/prevention & control , West Virginia/epidemiology
6.
A Tale of Silent Aspiration: Are Guidelines Good for Every Patient?
Kempen, Paul Martin.
Anesth Analg ; 121(3): 829-831, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26287304

Subject(s)
Pneumonia, Aspiration/diagnosis , Pneumonia, Ventilator-Associated/diagnosis , Female , Humans , Intubation, Intratracheal/adverse effects , Intubation, Intratracheal/methods , Middle Aged , Pneumonia, Aspiration/etiology , Pneumonia, Aspiration/therapy , Pneumonia, Ventilator-Associated/etiology , Pneumonia, Ventilator-Associated/therapy , Practice Guidelines as Topic/standards
7.
Insuring clear declaration of corporate conflicts of interest in all medical journals: the highest priority.
Kempen, Paul Martin.
J Clin Anesth ; 27(5): 434-5, 2015 Aug.
Article in English | MEDLINE | ID: mdl-25912727

Subject(s)
Anesthesiology , Conflict of Interest , Periodicals as Topic/standards , Humans , Peer Review, Research
8.
Corporate interests necessitate conflict of interest declarations by all authors.
Kempen, Paul Martin.
Anesthesiology ; 121(2): 431-2, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25050506

Subject(s)
Anesthesiology/education , Education, Medical, Graduate/standards , Educational Measurement/methods , Humans
9.
Maintenance of certification and licensure: regulatory capture of medicine.
Kempen, Paul Martin.
Anesth Analg ; 118(6): 1378-86, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24842183

Subject(s)
Certification/legislation & jurisprudence , Certification/trends , Licensure/legislation & jurisprudence , Licensure/trends , Anesthesiology/trends , Education, Medical, Continuing , Ethics, Research , Foreign Medical Graduates , Humans , Marketing , Physicians , Specialty Boards , Students, Medical , United States
10.
Perioperative ischemic optic neuropathy and spine surgery: are we asking the right questions?
Kempen, Paul Martin.
Anesthesiology ; 117(2): 431-2, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22828429

Subject(s)
Optic Neuropathy, Ischemic/prevention & control , Perioperative Care/methods , Spinal Diseases/surgery , Spine/surgery , Body Height , Body Mass Index , Female , Humans , Male , Posture , Risk Factors , Sex Factors
11.
Observations on the study of second gas effects.
Kempen, Paul Martin.
Anesthesiology ; 115(4): 900-1; author reply 902, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21934414

Subject(s)
Anesthesia Recovery Period , Anesthesia, Inhalation , Anesthetics, Inhalation/pharmacokinetics , Nitrous Oxide/pharmacokinetics , Female , Humans , Male
12.
Retrospective data review and propensity scoring: religion (believing) or science (proving) and the appropriate application of statistics.
Kempen, Paul Martin.
Anesthesiology ; 115(3): 656-7; author reply 657, 2011 Sep.
Article in English | MEDLINE | ID: mdl-21862891

Subject(s)
Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use , Postoperative Complications/prevention & control , Preoperative Care/methods , Vascular Surgical Procedures/methods , Female , Humans , Male
13.
Presenting data versus predictions as basic scientific information: target-controlled infusions versus microgram per kilogram per minutes.
Kempen, Paul Martin.
Anesthesiology ; 114(3): 721; author reply 721-3, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21343733

Subject(s)
Anesthetics, Intravenous/administration & dosage , Propofol/administration & dosage , Anesthetics, Intravenous/pharmacokinetics , Child , Consciousness Monitors , Electroencephalography , Humans , Infusions, Intravenous , Propofol/pharmacokinetics
14.
High-dose phenylephrine and ephedrine in obstetrics: proving the Holy Grail requires more data.
Kempen, Paul Martin.
Anesthesiology ; 112(5): 1285-7; author reply 1288-94, 2010 May.
Article in English | MEDLINE | ID: mdl-20418707

Subject(s)
Delivery, Obstetric , Ephedrine/administration & dosage , Phenylephrine/administration & dosage , Blood Pressure/drug effects , Blood Pressure/physiology , Delivery, Obstetric/methods , Drug Therapy, Combination , Ephedrine/adverse effects , Female , Humans , Infant, Newborn , Obstetrics/methods , Phenylephrine/adverse effects , Pregnancy
15.
Airway collapse or closure via the soft palate as mechanism of obstruction in sedated patients?
Kempen, Paul Martin.
Anesthesiology ; 112(2): 496; author reply 497, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20098144

Subject(s)
Airway Obstruction/etiology , Conscious Sedation/adverse effects , Palate, Soft/physiopathology , Airway Obstruction/physiopathology , Humans , Hypnotics and Sedatives , Monitoring, Intraoperative , Pharynx/physiopathology , Propofol , Respiratory Mechanics , Ventilators, Negative-Pressure
16.
Why should primary care physicians even wait for surgery in high risk patients?
Kempen, Paul Martin.
Anesthesiology ; 101(3): 801-2; author reply 804-6, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15329612

Subject(s)
Adrenergic beta-Antagonists/therapeutic use , Cardiovascular Diseases/prevention & control , Intraoperative Complications/prevention & control , Physicians, Family , Anesthesia , Humans , Risk
17.
Lidocaine administration, seizures, and causality.
Kempen, Paul Martin.
Anesthesiology ; 98(5): 1302-3, 2003 May.
Article in English | MEDLINE | ID: mdl-12717167

Subject(s)
Anesthetics, Local/therapeutic use , Epilepsy/drug therapy , Lidocaine/therapeutic use , Seizures/chemically induced , Adult , Anesthetics, Local/adverse effects , Anticonvulsants/therapeutic use , Female , Humans , Lidocaine/adverse effects
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