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Monoclon Antib Immunodiagn Immunother
; 35(2): 83-5, 2016 Apr.
Article
in English
| MEDLINE
| ID: mdl-26977890
ABSTRACT
A fluorescence immunoassay (FIA) has been developed for the detection of cocaine using norcocaine labeled with merocyanine dye and a monoclonal antibody specific to cocaine. Using this FIA, the detection range for cocaine was between 20.0 and 1700 µg/L with a limit of detection of 20.0 µg/L. Other cocaine derivatives did not interfere significantly with the detection when using this immunoassay technique with cross-reactivity values of less than 20%. Thus this FIA could be considered a useful tool for the detection of cocaine.