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J Craniomaxillofac Surg ; 37(8): 461-8, 2009 Dec.
Article in English | MEDLINE | ID: mdl-19674914

ABSTRACT

Gardner's syndrome (GS) is a hereditary autosomal dominant disease of the colon that presents with extra-colonic manifestations such as osteomas, skin lesions and dental abnormalities. Osteomas are commonly found in the skull, jaws and the paranasal sinuses. We present a family of four sisters affected with GS with a wide range of anomalies. The role of Cone beam computed tomography (CBCT) in the early detection and evaluation of osteomas and dental anomalies with precise assessment of their relationship to adjacent anatomic structures is described here in detail. The careful interpretation of CBCT may be of a great value in surgical and orthodontic treatment planning in the presence of jaw lesions. Management of dental problems in GS may be challenging due to the presence of odontomas and increased bone density. A multidisciplinary approach in the management of GS can achieve the best treatment results.


Subject(s)
Cone-Beam Computed Tomography , Gardner Syndrome/genetics , Osteoma/genetics , Patient Care Planning , Skull Neoplasms/genetics , Bone Density/physiology , Early Detection of Cancer , Female , Gardner Syndrome/diagnostic imaging , Gardner Syndrome/therapy , Humans , Malocclusion/diagnostic imaging , Malocclusion/genetics , Mandibular Neoplasms/diagnostic imaging , Mandibular Neoplasms/genetics , Maxillary Neoplasms/diagnostic imaging , Maxillary Neoplasms/genetics , Odontoma/diagnostic imaging , Odontoma/genetics , Osteoma/diagnostic imaging , Paranasal Sinus Neoplasms/diagnostic imaging , Paranasal Sinus Neoplasms/genetics , Skull Neoplasms/diagnostic imaging , Tooth Eruption, Ectopic/diagnostic imaging , Tooth Eruption, Ectopic/genetics , Tooth, Impacted/diagnostic imaging , Tooth, Impacted/genetics , Young Adult
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