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Curr Opin Mol Ther ; 5(1): 70-5, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12669474

ABSTRACT

Wilex AG, in collaboration with the Ludwig Institute for Cancer Research, is developing WX-G250, a kappa light chain chimeric antibody derived from the variable region of the mouse monoclonal antibody G250, for the potential treatment of biliary cancer and renal cell carcinoma (RCC). The antibody is currently undergoing phase II clinical trials for RCC and preclinical development for biliary cancer.


Subject(s)
Antibodies, Monoclonal/therapeutic use , Antibodies, Neoplasm/therapeutic use , Recombinant Fusion Proteins/therapeutic use , Animals , Antibodies, Neoplasm/immunology , Carcinoma, Renal Cell/therapy , Clinical Trials, Phase II as Topic , Gallbladder Neoplasms/therapy , Humans , Iodine Radioisotopes/therapeutic use , Kidney Neoplasms/therapy , Radioimmunotherapy , Recombinant Fusion Proteins/immunology , Technology Assessment, Biomedical
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