A hybrid machine learning feature selection model-HMLFSM to enhance gene classification applied to multiple colon cancers dataset.

Colon cancer is a significant global health problem, and early detection is critical for improving survival rates. Traditional detection methods, such as colonoscopies, can be invasive and uncomfortable for patients. Machine Learning (ML) algorithms have emerged as a promising approach for non-invasive colon cancer classification using genetic data or patient demographics and medical history. One approach is to use ML to analyse genetic data, or patient demographics and medical history, to predict the likelihood of colon cancer. However, due to the challenges imposed by variable gene expression and the high dimensionality of cancer-related datasets, traditional transductive ML applications have limited accuracy and risk overfitting. In this paper, we propose a new hybrid feature selection model called HMLFSM-Hybrid Machine Learning Feature Selection Model to improve colon cancer gene classification. We developed a multifilter hybrid model including a two-phase feature selection approach, combining Information Gain (IG) and Genetic Algorithms (GA), and minimum Redundancy Maximum Relevance (mRMR) coupling with Particle Swarm Optimization (PSO). We critically tested our model on three colon cancer genetic datasets and found that the new framework outperformed other models with significant accuracy improvements (95%, ~97%, and ~94% accuracies for datasets 1, 2, and 3 respectively). The results show that our approach improves the classification accuracy of colon cancer detection by highlighting important and relevant genes, eliminating irrelevant ones, and revealing the genes that have a direct influence on the classification process. For colon cancer gene analysis, and along with our experiments and literature review, we found that selective input feature extraction prior to feature selection is essential for improving predictive performance.

An investigation into the deep learning approach in sentimental analysis using graph-based theories.

Sentiment analysis is a branch of natural language analytics that aims to correlate what is expressed which comes normally within unstructured format with what is believed and learnt. Several attempts have tried to address this gap (i.e., Naive Bayes, RNN, LSTM, word embedding, etc.), even though the deep learning models achieved high performance, their generative process remains a "black-box" and not fully disclosed due to the high dimensional feature and the non-deterministic weights assignment. Meanwhile, graphs are becoming more popular when modeling complex systems while being traceable and understood. Here, we reveal that a good trade-off transparency and efficiency could be achieved with a Deep Neural Network by exploring the Credit Assignment Paths theory. To this end, we propose a novel algorithm which alleviates the features' extraction mechanism and attributes an importance level of selected neurons by applying a deterministic edge/node embeddings with attention scores on the input unit and backward path respectively. We experiment on the Twitter Health News dataset were the model has been extended to approach different approximations (tweet/aspect and tweets' source levels, frequency, polarity/subjectivity), it was also transparent and traceable. Moreover, results of comparing with four recent models on same data corpus for tweets analysis showed a rapid convergence with an overall accuracy of ≈83% and 94% of correctly identified true positive sentiments. Therefore, weights can be ideally assigned to specific active features by following the proposed method. As opposite to other compared works, the inferred features are conditioned through the users' preferences (i.e., frequency degree) and via the activation's derivatives (i.e., reject feature if not scored). Future direction will address the inductive aspect of graph embeddings to include dynamic graph structures and expand the model resiliency by considering other datasets like SemEval task7, covid-19 tweets, etc.