Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Acta Trop ; 165: 261-267, 2017 Jan.
Article in English | MEDLINE | ID: mdl-27887694

ABSTRACT

Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.


Subject(s)
Albendazole/therapeutic use , Anthelmintics/therapeutic use , Cysticercosis/drug therapy , Feces/parasitology , Sus scrofa/parasitology , Taenia solium/drug effects , Taeniasis/drug therapy , Animals , Cysticercosis/prevention & control , Enzyme-Linked Immunosorbent Assay , Humans , Laos/epidemiology , Pilot Projects , Prevalence , Swine , Swine Diseases/drug therapy , Swine Diseases/epidemiology , Swine Diseases/prevention & control , Taeniasis/epidemiology , Vaccination
2.
Acta Trop ; 159: 185-91, 2016 Jul.
Article in English | MEDLINE | ID: mdl-26992295

ABSTRACT

Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.


Subject(s)
Anthelmintics/therapeutic use , Swine Diseases/drug therapy , Swine Diseases/parasitology , Taenia solium/isolation & purification , Taeniasis/drug therapy , Taeniasis/prevention & control , Vaccination , Adult , Aged , Aged, 80 and over , Albendazole/therapeutic use , Animals , Benzimidazoles/therapeutic use , Cysticercosis/drug therapy , Cysticercosis/epidemiology , Cysticercosis/prevention & control , Enzyme-Linked Immunosorbent Assay , Feces/parasitology , Female , Humans , Laos/epidemiology , Male , Middle Aged , Pilot Projects , Prevalence , Swine , Swine Diseases/epidemiology
SELECTION OF CITATIONS
SEARCH DETAIL
...