[Intra-partum ethamsylate (dicynone) administration in the prevention of cerebral hemorrhage in premature infants]. / Intrapartum elkezdett ethamsylate (dicynone) kezelés a koraszülöttek agyvérzésének megelözésére.

Dicynone has been in use in all premature births prophylactically since 1987 by the authors. The administration of the drug begins before or during delivery. The diagnoses of cerebral haemorrhage was established on autopsy and the cases were compared with the previous years when Dicynone was not administered. During prophylactic use of Dicynone the cerebral haemorrhages significantly reduced among premature babies. It is well known, that the etiology of the cerebral haemorrhages are multifactorial. Their favourable experiences confirm the literary communications, whereas use of Dicynone can be one of the efficacious preventive drug against palsy of the premature babies.

Premature labor and coincident acute appendicitis not resolved by betamimetic but surgical treatment.

Three cases--one of them fatal--of betamimetic "resistant" premature labor with coincident acute appendicitis are presented. These case histories support the opinion held by the authors that in the recent era of widespread use of betamimetics, during the second and third trimester, appendicitis can be concealed by increased uterine contractility which could be secondary to the intra-abdominal inflammatory process or triggered by genuine premature motor activity of the myometrium. We consider that the obstetrician should revise his decision regarding betamimetic treatment on the basis of continuous observation. There is a clinical message in these cases which should be incorporated into the decision-making process: if a patient presents herself with premature labor, betamimetics should not be given before the diagnosis has been established.