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1.
Tech Hand Up Extrem Surg ; 23(4): 196-198, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31738740

ABSTRACT

Collagenase injections are used as a minimally invasive treatment for Dupuytren contracture of the palm and fingers, with good published success. Most complications are related to injection-site swelling, pain, and ecchymosis. However, the risk of flexor tendon and digital nerve injury can occur when injecting cords that cause proximal interphalangeal joint contractures. In addition, poor localization and incorrect injection of the solution into cords may result in an incomplete correction. We describe a technique to improve visualization and isolation of Dupuytren cords using a tongue depressor.


Subject(s)
Clostridium histolyticum/enzymology , Dupuytren Contracture/drug therapy , Injections, Intralesional/methods , Microbial Collagenase/therapeutic use , Equipment and Supplies , Humans
2.
Case Rep Orthop ; 2019: 7183739, 2019.
Article in English | MEDLINE | ID: mdl-31781455

ABSTRACT

Dupuytren's contracture is a disease involving abnormal myofibroblast proliferation and collagen deposition leading to the formation of pathologic cords in the hand. Given that Dupuytren's contractures rarely extend to the distal interphalangeal joint (DIP), affecting only 5% of patients, there are few cases reported in the literature. Collagenase injection is a frequently used option for minimally invasive treatment of Dupuytren's disease with greater than a 20-degree joint contracture. Unfortunately, there is limited research on the effectiveness of these injections in isolated DIP joint deformities. We present a case of a 61-year-old right hand-dominant male with a 2-year history of isolated right small finger Dupuytren's contracture at the DIP joint who achieved significant improvement after collagenase injection.

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