Retracted publications in autism research are mostly concerned with ethical misconduct.

BACKGROUND: As the prevalence of autism appears to increase, more research to guide effective diagnosis and intervention practices is needed. Findings disseminated through peer-reviewed publications are critical, but the number of retractions continues to rise. An understanding of retracted publications is imperative to ensure the body of evidence is corrected and current. OBJECTIVES: The objectives of this analysis were to summarize key characteristics of retracted publications in autism research, examine the length of time between publication and retraction, and assess the extent journals are adhering to publishing ethical guidelines for reporting retracted articles. METHODS: We searched five databases through 2021 (PubMed, EMBASE, Scopus, Web of Science, and Retraction Watch). RESULTS: A total of 25 retracted articles were included in the analysis. Ethical misconduct accounted for the majority of retractions rather than scientific error. The shortest time to retraction was 2 months and the longest length was 144 months. DISCUSSION: The time lag between publication and retraction since 2018 has improved considerably. Nineteen of the articles had retraction notices (76%), whereas six articles did not have a notice (24%). CONCLUSION: These findings summarize errors of previous retractions and illuminate opportunities for researchers, journal publishers and librarians to learn from retracted publications.

Trajectories of physical activity among autistic children and their caregivers: Outcomes of a virtual 1-year longitudinal intervention.

BACKGROUND: Participation in regular physical activity (PA) is a critical component of overall well-being. However, opportunities to engage in health-enhancing PA for families who have an autistic child are relatively obsolete. A virtual PA intervention has the potential to address many participation barriers and represents a timely opportunity to promote positive trajectories of PA among vulnerable populations. OBJECTIVE: To examine PA trajectories during a one-year virtual intervention for autistic children and their caregiver and to explore relationships in activity participation within child-caregiver dyads. METHODS: Twenty-nine families, including autistic children and their caregiver participated in the full intervention. Caregivers completed questionnaires to measure PA behavior at baseline and four-month intervals throughout the intervention. RESULTS: Reported PA significantly increased among autistic children and caregivers during the intervention. No association in PA was observed within dyads at baseline, but moderate relationships were observed during the intervention. CONCLUSION: Findings demonstrate the initial effectiveness of a virtual PA intervention for autistic children and their caregiver.

MYTime: A Mindfulness and Yoga Program to Promote Health Outcomes in Parents of Children With Autism Spectrum Disorder.

Background: Parenting a child with Autism Spectrum Disorder can be stressful and result in health consequences for the caregivers, a population that is often overlooked and underserved. While mind-body interventions such as mindfulness yoga can help promote positive health outcomes, limited research has explored the impact of such a program on caregivers of children on the autism spectrum. Objective: The primary objective of this pilot study was to evaluate the effects of a 12-week mindfulness yoga program (MYtime) on perceived stress, anxiety, and depression among urban caregivers of children on the autism spectrum. Methods: Twenty-seven parents were randomized into either MYTime (n = 13) or the control group (n = 14). Perceived Stress Scale (PSS) and Depression, Anxiety, and Stress Scale (DASS) were administered. Results: The MYTime group reported lower stress, depression and anxiety while the control group maintained similar scores across pre- and post-assessment. Following 12 weeks of participation the PSS and DASS scores improved by 25% and 49% respectively for parents in the MYTime group. In comparison, PSS scores worsened by 5% and DASS scores improved by 17% for the Control group. Differences in pre-and post-assessment scores were not significant for either group (P > .05). Conclusion: The results from this pilot study indicate that a mindfulness yoga program could be considered among feasible interventions aimed at improving the health of parents of children on the autism spectrum.

A-ONE - An Accessible Online Nutrition & Exercise Program For Youth with Physical Disabilities.

BACKGROUND: Pediatric disability prevalence has increased to 17.8% in recent years. This youth population faces a range of individual, social, and environmental level barriers to a healthy lifestyle. This is particularly concerning because this population is at a higher risk of obesity and lifestyle-related morbidity and mortality. Therefore, A-ONE: An Accessible and Online Nutrition & Exercise Program was designed to provide a comprehensive and holistic online program for youth with physical disabilities. METHODS: A-ONE will offer two individualized fitness workouts and one accessible cooking session per week for 16-weeks. In addition, A-ONE will offer one social-mentoring session per week. All programming (4 sessions per week) will occur during after-school hours. The program will be offered 6 times during the 2-year grant period, enrolling 10 youth per cohort, for a total of 60 youth with physical disabilities. Outcomes to be examined include physical activity, fruit and vegetable consumption, independent meal preparation, quality of life, and self-efficacy. They will be assessed pre, post, and 4-weeks following the end of the program. Program fidelity and feasibility will also be assessed. CONCLUSION: While children with physical disabilities benefit from opportunities to engage in physical activity and nutrition, accessible programming is unavailable. Despite decades of disability rights legislation mandating access to equal education, there is still a lack of system level solutions to improve the health inequity for youth experiencing disabilities. This program represents a sustainable and scalable way to remove barriers and improve the trajectories of health among youth with a physical disability.

Promoting physical activity participation and nutrition education through a telehealth intervention for children on the autism spectrum and their caregivers.

There is growing empirical support which suggests children on the autism spectrum, as well as their caregivers experience significant health disparities. The global COVID-19 pandemic has only magnified the need to address health among vulnerable populations. While there has been a growing trend in the delivery of telehealth interventions, the delivery of such methods for children on the autism spectrum, and their caregivers remains relatively under examined. The primary goal of PLANE (Physical Literacy And Nutrition Education) is to promote positive trajectories of health for children on the autism spectrum and their primary caregivers through the delivery of a telehealth physical activity and nutrition education program. The study is a pre-experimental analysis of PLANE across 12 months. All activities will be delivered virtually through weekly synchronous and asynchronous programming. A total of 180 participants will be enrolled in this intervention, including children on the autism spectrum and caregivers. Each week a new physical activity skill along with opportunities for recipe assembly will be delivered remotely. Supplemental material will be disseminated online including; step by step directions outlining behavioral skill methodology, opportunities for additional skill practice, and reading material that support weekly topics. Study outcomes will be examined in the parent-child dyad and include rates of overweight/obesity, physical activity, nutrition and quality of life. Finally, feasibility of the telehealth intervention will also be measured. Justification for the conceptualization and delivery of PLANE is well warranted, and PLANE represents a promising intervention which is scalable, sustainable, and replicable.

The Relationship Between Developmental Coordination Disorder and Concurrent Deficits in Social Communication and Repetitive Behaviors Among Children with Autism Spectrum Disorder.

Children with Autism Spectrum Disorder (ASD), characterized by core deficits in social communication and restrictive behaviors, can exhibit concurrent motor incoordination and/or intellectual disability (ID). While pervasive delays in motor behavior are common, formal diagnosis of Development Coordination Disorder (DCD) is uncommon. It is not clear how DCD and ID impact core deficits in ASD. This study utilized the Simons Foundation SPARK cohort to describe the scope of motor incoordination among children with ASD and examine the interrelationships between DCD risk, ID, and ASD core deficits. 10,234 children with ASD, between the ages of 5 and 15 years, were included in the analysis. Parents completed online versions of the DCD Questionnaire (DCD-Q), Social Communication Questionnaire (SCQ) and Restrictive Behavior Scale (RBS-R). 85% of children with ASD had DCD-Q scores consistent with being at-risk for DCD, but only 14% reported a formal diagnosis. Children with ID exhibited significantly greater motor incoordination compared to children without ID (P < 0.001). Significantly, greater core deficits were identified in both children at-risk for DCD (P < 0.001) and with ID (P < 0.001). However, the effects of DCD risk were independent of ID and exhibited a medium effect size for SCQ (η2p = 0.063) and a small effect size for RBS-R (η2p = 0.04) scores. Collectively, study outcomes reinforce the pervasiveness of motor incoordination among children with ASD, both with and without concurrent ID, and provide further justification for the inclusion of motor behavior in the early intervention and prescription for children with ASD. LAY SUMMARY: This secondary data analysis of the Simons Foundation SPARK cohort found high rates (85%) of DCD risk among children with ASD. Deficits in motor coordination were greater among children with ASD with concurrent ID diagnoses. Meaningful differences in ASD core deficits (social communication and repetitive behaviors) were independently found in children at risk for DCD, both with and without ID. Autism Res 2021, 14: 804-816. © 2021 International Society for Autism Research and Wiley Periodicals LLC.

Physical activity and motor skill outcomes of a 10-week intervention for children with intellectual and developmental disabilities ages 4-13: A pilot study.

BACKGROUND: Children with intellectual and developmental disabilities (IDD) often experience increased barriers to engaging in physical activity (PA) which can stem from lack of gross motor function (GMF) development. Intervening on GMF at an early age can create better opportunities for children with IDD to engage in regular PA. In turn, increased PA can improve health outcomes and increase social skills. OBJECTIVE: The primary objective of this pilot study was to explore the effectiveness of a community-based GMF-focused PA intervention for improving overall motor skills and PA for children with IDD. METHODS: All study participants (n = 24) engaged in 10 weeks of programming for 1 h each week. A convenience sample was utilized. RESULTS: Results indicated no statistically significant changes pre to post for motor skill scores. However, a visual analysis of mean changes showed a consistent pattern of increased scores from pre to post on most skills. Additionally, we found that a change in participant locomotor skills significantly predicted change in Moderate to Vigorous Physical Activity (MVPA), F (1,11) = 5.16, Adj R2 = .26, p = .04. CONCLUSIONS: These results suggest individualized attention on GMF may help to increase motor skills for children with IDD. This study adds to the small but growing amount of research examining the efficacy of community based adapted PA interventions. Further, study results should support continued exploration of effective approaches to address the motor delays experienced by children with IDD.

Minimum Accelerometer Wear Time in Infants: A Generalizability Study.

BACKGROUND: Research measuring physical activity behaviors during infancy is critical for evaluation of early intervention efforts to reduce rapid weight gain. There is little known about the physical activity patterns of infants, due in part to limited evidence for measurement procedures. This study sought to determine the minimal number of days and hours of accelerometry needed to reliably measure daily physical activity in infants using Generalizability (G) theory. METHODS: A total of 23 infants (14 female, 9 male) wore an accelerometer on the right ankle and right wrist for 7 days. Data were manually cleaned to remove activity counts not produced by the infant. G theory analyses were conducted on the average counts per epoch. RESULTS: Reliable estimates were observed with at least 2 days (G & Φ = .910) and 12 hours (G = .806, Φ = .803) at the ankle, and with at least 3 days (G & Φ = .906) and 15 hours (G = .802, Φ = .800) at the wrist. CONCLUSIONS: These results provide some of the first guidelines for objective physical activity measurement during infancy. Accelerometer monitoring periods of at least 3 days including all daytime hours appear to be sufficient for reliable measurement.

Methodology to Promote Physical Activity Monitoring Adherence in Youth with Autism Spectrum Disorder.

BACKGROUND: Objective physical activity (PA) monitoring via accelerometry is both costly and time consuming. Furthermore, overall adherence to a monitoring protocol is often complicated by disability. Therefore, it is essential that strategies for supporting accelerometer wear for youth with disabilities are maximized. The purpose of this perspective was to provide researchers a set of efficacious PA monitoring strategies based on the retrospective examination of support methodology on adherence rates for youth with autism spectrum disorder (ASD). METHOD: Accelerometer data were collected from 163 participants with ASD in three independent cohorts. Each cohort was provided a varying set of support strategies to help maximize adherence. Chi-square analysis was used to determine differences in adherence between each cohort. RESULTS: Adherence rates significantly increased from 51.9% in cohort 1 to 88.7% in cohort 2 [χ2(1) = 18.333, p < 0.001] and again from 88.7% in cohort 2 to 97.4% in cohort 3 [χ2(1) = 2.663, p = 0.103]. The greatest increase in adherence was observed from 51.9% in cohort 1 to 97.4% in cohort 3 [χ2(1) = 19.837, p < 0.001]. Support strategies associated with these increases included (1) social story, (2) incentive, (3) concealing techniques, and (4) 24 h/day wear instructions. CONCLUSION: Adherence to PA measurement increased when additional support strategies were utilized in combination with a traditional protocol. We recommend these support methodology to be considered as preliminary best practices when measuring objective PA in youth with ASD with likely success in other disability populations.