ABSTRACT
Thyroid carcinoma is the most common primary cancer of the thyroid gland. The purpose of the study is to find if thyroid gland carcinoma show gender predilection in Armenia. 529 cases of thyroid gland cancer were studied in hospitals from 1999 to 2011. It was found that thyroid gland carcinoma is three times more common in women than in men practically in all age groups. In comparison with 1985 year the frequency of disease in women has increased. Thyroid gland carcinoma had a higher death rate in women than in men. The lethality was higher in men.
Subject(s)
Sex Factors , Thyroid Neoplasms/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Armenia/epidemiology , Female , Humans , Male , Middle Aged , Neoplasm MetastasisABSTRACT
Thyroid cancer is considered as one of the deadly cancers. Differentiation of benign and malignant structures is difficult in patients with thyroid cancer. This work is devoted to the problem of early clinical diagnosis of thyroid cancer. 523 cases of primary thyroid cancer from 1999 to 2011 were studied. The pathomorphologic analysis of thyroid cancer was carried out. The problem of early detection of thyroid cancer is reviewed. It is concluded that the thyroid nodule fine-needle aspirate biopsy and intraoperative frozen section examination do not allow the accurate differentiation of benign tumours from malignant neoplasms; novel diagnostic methods for early detection of thyroid cancer are needed.
Subject(s)
Adenoma/diagnosis , Biopsy, Fine-Needle/methods , Diagnosis, Differential , Thyroid Gland/pathology , Thyroid Neoplasms/diagnosis , Adenoma/pathology , Humans , Thyroid Neoplasms/pathology , Thyroid Nodule/diagnosis , Thyroid Nodule/pathologyABSTRACT
The aim of the research was the analysis of metastasis in patients with thyroid carcinoma in Armenia in 1999-2011. Case histories of 529 patients with thyroid cancer from 1999-2011 were investigated. It was found that the prognostic value of regional metastases differs considerably. In cases of differentiated carcinomas the regional metastases are not regarded as a significant factor of the prognosis, because the majority of the affected lymph nodes is removed by the qualified surgeons during the operation, and the others (not revealed or micrometastases), due to ability to accumulate radio iodine, can be liquidated in the postoperative course of radio iodine therapy. The prognosis is less favorable in regional metastasizing at patients with other types of thyroid cancer. Almost the half of the patients who have died because of thyroid carcinoma had the regional and distant metastases. The index of metastasis in thyroid cancer in rural settlements is higher, than in urban in Armenia. The frequency of metastasizing is higher in elderly patients.
Subject(s)
Neoplasm Metastasis , Thyroid Neoplasms/epidemiology , Thyroid Neoplasms/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Bone Neoplasms/epidemiology , Bone Neoplasms/secondary , Female , Humans , Liver Neoplasms/epidemiology , Liver Neoplasms/secondary , Lung Neoplasms/epidemiology , Lung Neoplasms/secondary , Lymph Nodes/pathology , Male , Middle AgedABSTRACT
The aim of the study was the evaluation of early diagnosis of thyroid cancer and its impact on the management of these patients. Hospital-based study of 113 primary thyroid cancer cases diagnosed between 1999 and 2011 were evaluated in this report. The study revealed the crucial importance of accurate information about the subtypes of thyroid tumors in the management of these patients and the prognosis of thyroid cancer. There is need for reproducible biomarker that correlates directly with the presence or progression of thyroid cancer.
Subject(s)
Early Diagnosis , Thyroid Neoplasms/diagnosis , Biomarkers, Tumor , Humans , Prognosis , Thyroid Neoplasms/pathologyABSTRACT
The object of this report is to inform the traumatologists on some problems of the bone micro-destruction, which can be important for diagnosis, selection of fracture treatment tactics and complication prophylaxis. The obtained results can be used in practice.
