[Influence of microwave and laser radiation on survivability of organisms]. / Vliianie mikrovolnomogo i lazernogo izlucheniia na zhiznesposobnosts' organizmov.

Depending on energy, spatial-temporal, modulation and other characteristics of an electromagnetic field, properties of a subject, exposure settings and possible interaction of other attendant factors microwaves may have either stabilizing, wholesome and even therapeutic or negative (damaging) effects on biological and ecological objects and systems. Therefore, there are two interrelated problems to be addressed. One is electromagnetic safety of and health provisions for humans exposed to EMF and EMR and the other, effective utilization of microwave EMF and EMR for biomedical and other purposes associated with enhancement of viability of organisms. The light-oxygen effect of laser radiation is gaining footing in therapy where it is used to activate or destroy biological systems by optical radiation at a specified light dose. Thus, low-intensity laser radiation can be used to improve viability and high-intensity laser radiation, to treat cancers.

[Ecological zones of Dagestan territory and epidemiology od acute leukemia in older age groups]. / Ekologicheskoe zonirovanie territorii Dagestana i épidemiologiia ostrykh leikozov v starshikh vozrastnykh gruppakh.

The authors report annual acute leukemia incidence through 1980 to 1995 in Dagestan in respect of implications of of environmental factors. The highest leukemia incidence rate was in the age group over 50 years. Acute leukemia incidence varied with years, sex and territory zones. Active utilization of chemical fertilizers in agriculture proved a contributing factor in the onset of acute leukemia, especially in persons older than 50 years.

[Mechanisms of biophysical effects of microwaves]. / Mekhanizmy biofizicheskogo deistviia mikrovoli.

According to our and other investigators theoretical and experimental dates biophysical effects of microwaves are defined by thermal and specific biological action. Specific influence are realized by more delicate and precise ways and mechanisms of absorption and molecular relaxation of microwave energy, energy-informative interaction of radio-emission with biosystem. It include three mechanisms: synchronisation of oscillatory processes (oscillators) of irradiated object in acting electromagnetic field; selective influence of microwaves on the biomembranes, on nervous and other highly-organized systems of living organism, on the complex formation processes and fermentative activity; resonance phenomena. These mechanisms connected with parameters of acting electromagnetic field and with electrical, magnetic and other properties of biological systems.

[Characteristics of sodium metabolism in rats with experimental hypertension caused by chronic alimentary imbalance]. / Osobennosti obmena natriia u krys s éksperimental'noi gipertenziei, obuslovlennoi khronicheskim alimentarnym disbalansom.

Beginning from 1.5 month of life Wistar rats were kept under conditions of chronic 1 and 2% salt loading combined with a low-protein diet (6-8% of protein VS, as compared with 23-24% in the normal diet). At the age of 14-16 months when a stable hypertension developed due to the above alimentary imbalance, their sodium metabolism was studied using whole-body radiometry with 22Na. A three-chamber model of 22Na metabolism was developed for the analysis of 22Na excretion from the body. This helped in establishing the heterogeneity of sodium metabolism in experimental animals. Besides that, it has been shown that not only sodium retention in the body, but also its redistribution between intra- and extravascular sections play an important role in the development of hypertension. Protein deficiency in the diet aggravates sodium metabolism disorders in experimental animals.

[Neuroleptanalgesia, surgical trauma and immunity]. / Neiroleptanalgeziia, operatsionnaia travma i immunitet.

Immune status and hormonal homeostasis have been studied in 26 patients with larynx cancer operated on (laryngectomy, extended laryngectomy) under neuroleptanalgesia. It has been established that 3 and 7 days after the operation there was a decrease in plasma cortisol level and an increase in B- and T-lymphocyte count and theophylline-resistant T-lymphocyte count in the peripheral blood. In 4 patients with postoperative complications (pharyngeal fistulas) there was a reverse correlation between cortisol content and B-lymphocyte count and T-lymphocyte blast transformation.

[Sodium metabolism in Wistar rats exposed to chronic isotonic salt load after preliminary protein deficiency in the diet according to radiometry of the whole body with 22-Na]. / Obmen natriia u krys vistar v usloviiakh khronicheskoi izotonicheskoi solevoi nagruzki posle predvaritel'nogo defitsita belka v diete po dannym radiometrii vsego tela s 22Na.

The long-term preliminary protein deficiency in the diet gives rise to irreversible changes in sodium metabolism in experimental animals exposed subsequently to chronic salt load combined with full-value feeding. Apparently such changes do not go, however, beyond the compensatory potentialities of the body exposed to isotonic salt load, since the systolic arterial pressure does not undergo any material changes throughout the whole experiment.

[Characteristics of sodium metabolism in Wistar rats in relation to the uptake of sodium chloride studied by whole body Na-22 radiometry]. / Osobennosti obmena natriia u krys linii Wistar v zavisimosti ot urovnia potrebleniia povarennoi soli po dannym radiometrii vsego tela s radionuklidom 22Na.

The rate of sodium elimination was shown to be inadequate to sodium uptake in rats exposed to prolonged salt loading, the higher the load, the greater the inadequacy. Sodium distribution between vascular and extravascular spaces of the body was also disproportionate in conditions of both excessive and low sodium uptake.

[Modeling of experimental hypertension by chronic salt loading combined with a low-protein diet in Wistar rats]. / Modelirovanie eksperimental'noi gipertonii s pomoshch'iu khronicheskoi solevoi nagruzki v sochetanii s nizkobelkovoi dietoi u krys Vistar.

Combination of chronic salt loading with protein-poor diet produces experimental hypertension with natrium consumption near to physiological. The present model is characterized, compared to the existing one, by stage development, moderate arterial blood pressure elevation and absence of "salt toxicosis" and may be thus considered more adequate for experimental investigation of primary arterial hypertension pathophysiology.

[Effect of peritol on the functional and morphological characteristics of the small intestine in rats]. / Vliianie peritola na funktsional'nye i morfologicheskie kharakteristiki tonkoi kishki krys.

Experiments were made on 140 male Wistar rats with the use of morphological, biochemical and radiometric research methods. It was established that as soon as the treatment with the anabolic drug peritol was completed, there appeared the morphological signs attesting to an increase in functional activity of vasculostromal elements of the small intestine, and the absorption rate of vitamin B12 got intensified. Activity of enzymes responsible for parietal digestion (alkaline phosphatase, invertase), absorption of 59Fe-citrate and 131I-albumin were unchanged. No substantial changes were revealed on the part of the morphology and function of the small intestine in the long-term period after peritol administration.

[57Co-bleomycetin pharmacokinetics in the body of mice with LIO-1 lymphosarcoma]. / Farmakokinetika 57Co-bleomitsetina v organizme myshei s limfosarkomoi LIO-1.

Pharmacokinetics of 57Co-bleomycetin was studied on mice with lymphosarcoma LIO-1. It was found that at early periods of intravenous administration of the labeled antibiotic, i.e. within the period from 5 minutes to 1 hour its higher levels are detected in the liver, kidneys, blood serum, lungs, intestine and tumor. At later periods the drug levels in the organs and tissues gradually decrease and by the 72nd hour the concentration of 57Co-bleomycetin in the blood serum appears to be 30 times lower as that after 5 minutes. In the muscles and tumor its concentrations by that period are 15 and 2 times lower respectively. Radiometry of the animals showed that within the first 24 hours more than 85 per cent of 57Co-bleomycetin was excreted from the mice.