Retrospective Analysis of Dental Implant Failure Rates in Patients with Compromised Health.

Objectives: The goal of the current research was to compare the failure rate of dental implants in medically compromised patients to healthy individuals. Materials and Methods: In this seven years retrospective study, 50 patients from Group A who were medically compromised had 63 implants, while 50 patients from Group B who were healthy had 67 implants. Over 1 mm of bone loss around the implant in the first year and over 0.2 mm of bone loss per year after that were considered failure rates. Result: Two (2.9%) of the dental implants in Group B and 18 (28.6%) in Group A, both failed. The average bone loss around the implant in Group A during the first year was 1.21 mm, compared to 0.3 mm in Group B. Conclusion: Uncontrolled diabetes mellitus group had greater implant failure.

Effect of periostin in peri-implant sulcular fluid and gingival crevicular fluid: A comparative study.

Background: Various similarities have been observed between gingival crevicular fluid (GCF) and peri-implant sulcular fluid (PISF). This has resulted in research that has evaluated similar biological fluid markers that are similar to those present within the gingival sulcus. These biomarkers have high sensitivity and are a reliable biological tool when compared to clinical and/or radiographic examination and aid in diagnosis as well as monitoring the progression of periodontal disease surrounding teeth as well as the implants. Aim: The study aimed to compare the effectiveness of periostin in peri-implant sulcular and gingival crevicular fluids. Materials and Methods: This experimental prospective in vitro analysis was done following clearance by the institutional ethical committee. A total of 100 patients were selected. They were categorized into two groups: (I) Group A patients had peri-implant disease (n = 50), whereas (II) Group B patients had periodontitis (n = 50). Clinical loss of attachment score was noted in six sites around natural teeth and four sites around the implants. Presterilized filter paper strips were inserted within the sulcus/pocket till pressure was felt for 60 s. Periostin concentration levels in GCF and PISF samples were measured by the enzyme-linked immunosorbent assay technique. Statistical analysis of data collected was performed using Shapiro-Wilk statistical tool for normally distributed numerical data. . Results: Mean ± standard deviation concentration of periostin in gingival crevicular fluid from periodontitis cases was recorded as 20.15 ± 2.76 ng/30sn, whereas in PISF was 19.23 ± 1.89 ng/30sn. On statistical analysis, no statistically significant differences were seen after comparing the concentration of periostin in periodontitis as well as peri-implantitis groups (P > 0.05). Conclusion: The present study analyzed periostin levels in gingival crevicular fluid obtained from patients diagnosed with periodontitis and sulcular fluid obtained from the sulcus around implants. Early biological markers or indicators of inflammation should be studied to determine the prognosis of treatment apart from the clinical assessment for the patient's benefit.

Résumé Contexte: Diverses similitudes ont été observées entre le fluide sulculaire gingival (GCF) et le fluide sulculaire péri-implantaire (PISF). Ce a abouti à des recherches qui ont évalué des marqueurs fluides biologiques similaires à ceux présents dans le sillon gingival. Ces les biomarqueurs ont une sensibilité élevée et sont un outil biologique fiable par rapport à l'examen clinique et/ou radiographique et aident à diagnostic ainsi que le suivi de la progression de la maladie parodontale entourant les dents ainsi que les implants. Objectif: L'étude visait à comparent l'efficacité de la périostine dans les fluides péri-implantaires sulculaires et gingivaux. Matériels et Méthodes: Ce test expérimental une analyse prospective in vitro a été effectuée après autorisation par le comité d'éthique de l'établissement. Au total, 100 patients ont été sélectionnés. Ils étaient classés en deux groupes: (I) les patients du groupe A avaient une maladie péri-implantaire (n = 50), alors que (II) les patients du groupe B avaient une parodontite (n = 50). Le score clinique de perte d'attache a été noté dans six sites autour des dents naturelles et quatre sites autour des implants. Bandes de papier filtre préstérilisées ont été insérés dans le sulcus/poche jusqu'à ce que la pression soit ressentie pendant 60 s. Les niveaux de concentration de périostine dans les échantillons GCF et PISF ont été mesurés par la technique de dosage immuno-enzymatique. L'analyse statistique des données recueillies a été effectuée à l'aide de la méthode statistique de Shapiro-Wilk. outil pour les données numériques distribuées normalement. Résultats: concentration moyenne ± écart-type de périostine dans le liquide gingival les cas de parodontite ont été enregistrés à 20,15 ± 2,76 ng/30sn, alors que dans le PISF, ils étaient de 19,23 ± 1,89 ng/30sn. Sur l'analyse statistique, pas statistiquement des différences significatives ont été observées après avoir comparé la concentration de périostine dans les groupes parodontite et péri-implantite (P > 0,05). Conclusion: La présente étude a analysé les niveaux de périostine dans le liquide créviculaire gingival obtenu chez des patients diagnostiqués avec une parodontite et fluide sulculaire obtenu à partir du sulcus autour des implants. Les marqueurs ou indicateurs biologiques précoces de l'inflammation doivent être étudiés pour déterminer le pronostic du traitement en dehors de l'évaluation clinique au bénéfice du patient. Mots-clés: Créviculaire, liquide, gingival, péri-implantaire, parodontite, périostine, pronostic, sulculaire.

Demineralized Freeze-Dried Bone and Modified Hydroxyapatite Granules in Patients Requiring Immediate Dental Implants: A Comparative Study.

Objectives: The objective is to compare demineralized freeze-dried bone and modified hydroxyapatite granules in patients requiring immediate dental implants. Materials and Methods: Forty patients for immediate dental implants were divided into Group I (demineralized freeze-dried bone allograft) and Group II (modified hydroxyapatite) based on the type of graft used. Success of graft was evaluated based on modified plaque index, gingival index, and Periotest at 3, 6, and 12 months follow up. Results: The mean modified plaque index, gingival index, peri-implant sulcular depth, and Periotest were recorded at baseline, 3, 6, and 12 months at implant site and full mouth in both groups found to be nonsignificant (P > 0.05). Conclusion: Both demineralized freeze-dried bone allograft and modified hydroxyapatite grafts were equally efficient in immediate dental implant placement sites.

Botulinum Toxin Application in Facial Esthetics and Recent Treatment Indications (2013-2018).

BACKGROUND: Ever-changing perception of beauty from childhood to old age is changing with the revolution in cosmeceuticals science. Esthetics is an individual's perception since time immemorial. Standards of beauty have changed through centuries with increased awareness about esthetics. The face remains main source of information for identification and discrimination. It constitutes a structural ground for many nonverbal messages including the emotional state of a person, so the proverb "Face is an index of mind" holds good. The wrinkles and laxity are considered to be one of the factors for aging. Hence, escalating demand for cosmetic treatment to reduce facial wrinkles and laxity has stimulated us to search for published literature for nonsurgical techniques for enhancement of facial beauty. The review analyzed the published data to provide narrative basic review in a concise way to the beginners, clinicians, and students. MATERIALS AND METHODS: We have adopted search criteria using keywords: Botox, Botulinum toxin, incobotulinumtoxinA, esthetics, face, uses of Botox, with various Boolean operators and or in title, and abstract using PubMed search engine. The database search limited to PubMed only from January 2013 to June 2018. RESULTS: Various search results have been appended as annexures at the end of the article for further reference for the readers. Finally, 17 references were selected to write narrative review to meet our objectives. CONCLUSION: The advancing front in the use of toxins is an emerging science for the beautification of a face. Botox exploded in to market because of efficacy, tolerability, and minimally invasive nature. The present review gives brief about the history of Botulinum toxin, types, mechanism of action, clinical indications, preparations, storage, and technique for various uses with a brief note on patient selection, contraindications, and complications.