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1.
Probl Tuberk ; (4): 3-7, 1990.
Article in Russian | MEDLINE | ID: mdl-2118642

ABSTRACT

The rate of mucociliary transport (MCT) in dogs with an experimental pulmonary tuberculosis and concurrent suppurative endobronchitis (SEB) and just with the latter was measured. The treatment effect was achieved by an endobronchial radiation with a CO2-laser unfocused beam of 3.56 and 5.3 w/cm2 power density, and the dogs in the control group were subjected to an endobronchial introduction of furagin. A comparison of the endoscopic picture and MCT rate findings made it possible to believe that the latter index appeared to be more reliable than a visual inspection of the bronchial mucous membrane. An active specific process in the lungs brings about MCT rate inhibition while the concurrent SEB aggravates these changes to a great extent. The radiation of the bronchial mucous membrane with the CO2-laser unfocused beam produces an immediate positive effect on MCT rate normalization. Better results were observed at a power density of 3.56 w/cm2.


Subject(s)
Bronchi/radiation effects , Bronchitis/radiotherapy , Laser Therapy , Mucociliary Clearance/radiation effects , Tuberculosis, Pulmonary/radiotherapy , Animals , Bronchi/physiopathology , Bronchitis/physiopathology , Carbon Dioxide , Dogs , Mucociliary Clearance/physiology , Time Factors , Tuberculosis, Pulmonary/physiopathology
2.
Probl Tuberk ; (8): 61-4, 1989.
Article in Russian | MEDLINE | ID: mdl-2813316

ABSTRACT

The structure of the ciliated epithelium and its regeneration under normal conditions were studied using biopsy specimens of the trachea and extrapulmonary bronchi from healthy dogs. The specimens were processed with the routine methods for electron microscopy. Along with the typical structure of the ciliated cells there were observed various deviations considered earlier as consequences of bronchopulmonary pathology: changed cytoplasm of the ciliated cells in the form of cytoplasmic processes or follicles. In their composition there were single cilia, their aggregates and secretory granules. The qualitative and quantitative changes in the cilia were in the form of cilia with excessive cytoplasm, cilia aggregates included in a common cuticula, etc. It was suggested that the changes in the ultrastructure of the bronchial epithelium reflected a definite stage of the cell development and represented the normal state variants.


Subject(s)
Bronchi/ultrastructure , Animals , Cilia/ultrastructure , Cytoplasm/ultrastructure , Cytoplasmic Granules/ultrastructure , Dogs , Epithelium/ultrastructure , Microscopy, Electron , Trachea/ultrastructure
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