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2.
Radiobiologiia ; 29(5): 644-7, 1989.
Article in Russian | MEDLINE | ID: mdl-2587702

ABSTRACT

In experiments with rats and mice irradiated with doses of 5 and 8.5 Gy respectively, the radioprotective properties of a coordination combination Co(III) with bioactive ligands have been investigated by the results of the hematological analysis, the indices of erythrocyte and leucocyte electric conductivity, average life, survival rate, and beta coefficient showing a probability of protecting the organism against fatal effect of ionizing radiation. The preparation has either therapeutic or protective action depending on the animal species and radiation dose.


Subject(s)
Cobalt/therapeutic use , Organometallic Compounds/therapeutic use , Radiation-Protective Agents/therapeutic use , Animals , Cobalt/toxicity , Erythrocyte Count , Hemoglobins/analysis , Leukocyte Count , Male , Mice , Organometallic Compounds/toxicity , Radiation Injuries, Experimental/blood , Radiation Injuries, Experimental/drug therapy , Radiation Injuries, Experimental/prevention & control , Rats
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