[Primary focal segmental glomerular sclerosis in children: epidemiology and prognosis]. / Hyalinose segmentaire et focale primitive de l'enfant : épidémiologie et facteurs pronostiques.

Focal segmental glomerulosclerosis (FSGS) is the morphologic description of a glomerular lesion which is "focal", meaning a few but not all of the total sampled glomeruli have and "segmental" solidification of the tuft that is an accumulation of extracellular matrix with obliteration of the capillary lumina (sclerosis). It represents 20% of nephrotic syndrome in children and adults. To study the role of epidemiology, clinical presentation, histology, and treatment in the prognosis of HSF child, we retrospectively analyzed 23 children with primary focal segmental glomerulosclerosis (FSGS) hospitalized in pediatric nephrology unit of Children's Hospital Harrouchi Abderrahim, CHU Ibn Rochd Casablanca from January 2000 to December 2012. The main age at onset was 7.5 years with a male predominance. Hematuria was seen in 22% of patients, hypertension in 48% of patients, and moderate renal insufficiency in one patient at presentation. According to the histological classification of Columbia, 40% of patients have a non-specific HSF (NOS), including six patients who have responded to treatment and one patient progressed to renal failure, 13% have a perihilar HSF (PH) with a good prognosis, 8% have a HSF cell (CELL), which evolved to renal failure, 35% of HSF was a tubular pole (TIP) including five patients responded to treatment and 4% was a HSF collapsing (COL) having a renal failure at admission. The FSGS's prognosis is related to several predictive factors.

A rare cause of painful cervical swelling: myositis ossificans progressiva in childhood. Report of a case.

Myositis ossificans progressiva (MOP) is a rare condition of which we report a case in a 13-year-old girl with involvement of the cervical paraspinal and periscapular muscles. No ectopic ossifications were visible on plain radiographs. Computed tomography disclosed diffuse inflammation. Plain radiographs of the toes confirmed the diagnosis by visualizing characteristic bone abnormalities. Knowledge of the digital abnormalities seen in MOP is important to avoid unnecessary diagnostic investigations, most notably a surgical biopsy, which may trigger a flare of the disease. The prognosis is guarded.

[Primary peritonitis in children with nephrotic syndrome]. / Péritonite primitive de l'enfant dans le syndrome néphrotique.

The primitive peritonitis (PP) is one of the rare but severe complications of the nephrotic syndrome. Through a series of 25 children who suffer from a primitive peritonitis complicating or revealing a nephritic syndrome, we tried to analyse the epidemiological and bacteriological aspects of these peritonitis. The mean age of the children is 7 years old with neat male predominance (3 boys/1 girl). Two patients presented 2 episodes of PP. In 16% of the cases, the PP revealed a nephrotic syndrome. The isolated germs in our series are the Escherichia coli (45.5%) and the pneumococcus (36.5%), in 56% of the cases, the germ has not been identified. The precocious large use of probabilist antibiotherapy permitted a favourable evolution with nil rate of mortality.