ABSTRACT
The present study was conducted to reveal the pattern of different gastrointestinal malignant neoplasms in Alexandria in the last decade (1987-1996). All registered cases of GIT cancers in Alexandria. Main University Hospital in the last decade were included in the study. The results revealed that the total number of cases was 2184, 58.6% were males and 41.4% were females. The mean age of registered cases was significantly older among males than females (t = 2.43). The highest percentage (47.2%) of cases were in the age group (40- < 60 years). Less than quarters (73.3%) of the total cases have had malignant neoplasms of digestive organs and 26.7% have had malignant neoplasms of lips, oral cavity and pharynx. Of the latter category cancer pharynx came first in both sexes (49.9%) with the youngest mean age (45.65 +/- 15.79 years), followed by cancer tongue (24.9%) with the oldest mean age (58.56 +/- 12.4). Among cases of malignant neoplasms of digestive organs, cancer colon came first in both sexes (26.9%) with the youngest mean age (44.11 +/- 14.08 years). Cancer gall bladder came last (1.2%) with the oldest mean age (55.80 +/- 10.20 years). Over the last decade trend of malignant neoplasms of colon, rectum, liver and pancreas were increasing while the reverse was observed for cancer oesophagus and stomach. So it is necessary to plan for GIT cancer control programme.
Subject(s)
Gastrointestinal Neoplasms/epidemiology , Urban Health/trends , Adolescent , Adult , Age Distribution , Aged , Cause of Death/trends , Egypt/epidemiology , Environmental Exposure/adverse effects , Female , Gastrointestinal Neoplasms/etiology , Gastrointestinal Neoplasms/prevention & control , Health Planning , Health Services Needs and Demand , Hospitals, University , Housing/trends , Humans , Male , Middle Aged , Population Surveillance , Registries , Residence Characteristics/statistics & numerical data , Retrospective Studies , Risk Factors , Sanitation/trends , Sex Distribution , Smoking/adverse effectsABSTRACT
Twenty five non-atopic scabietic patients were examined to estimate their reaction to crude house dust mite Dermatophagoides farinae (D. farinae) and storage mite Tyrophagus putrescentia (T. putrescentiae) antigens. Skin prick testing (SPT) by extracts of both mites antigens showed significant higher positive results in scabietics when compared to non-scabietic control subjects. Moreover, 60% and 56% of scabietic patients showed positive levels of specific anti-D. farinae and T. putrescentia IgE respectively in comparison to 13.4% & 20% of control subjects. A significant difference has been obtained when the total number of positive results were compared to the total number of negative ones. The results revealed that there is an evidence of cross reactivity between Sarcoptes scabiei antigens and extracts of D. farinae and T. putrescentiae, and the hypersensitivity to house dust mite and storage mite antigens was significantly higher in scabietics than in controls. It could be concluded that there is some proof that other mites rather than Sarcoptes scabiei may have a role in the pathogenesis of scabies and the cross reactivity between S. scabiei and house dust mite and storage mite may explain the persistence of symptoms in some cases even after proper treatment of the disease.
Subject(s)
Antigens/immunology , Hypersensitivity, Immediate/complications , Mites/immunology , Sarcoptes scabiei/immunology , Scabies/complications , Adolescent , Adult , Animals , Child , Child, Preschool , Cross Reactions , Dust , Female , Humans , Hypersensitivity, Immediate/immunology , Immunoglobulin E/blood , Male , Middle Aged , Scabies/immunologyABSTRACT
A total of 300 women nursing a child aged 6 to 24 months were interviewed to determine their sociodemographic and biological characteristics, the antenatal care received, health problems encountered during pregnancy and the postpartum period, breast-feeding practices, child nutrition, and the duration of postpartum amenorrhoea. Multivariate Cox regression analysis revealed that seeking antenatal care, the time of initiation of breast-feeding, and the infant's age at the time of supplement introduction were the only significant independent determinants of the duration of the lactational amenorrhoea. To prolong the duration of lactational amenorrhoea, health education regarding good breast-feeding practices is of crucial value
