ABSTRACT
AIMS: Many veterans of the 1990-1991 Gulf War Era (GWE) have experienced poorly understood health issues. In response to challenges recruiting this population for research, we conducted focus groups and semi-structured phone interviews with GWE veterans and subject matter experts (SMEs) to explore GWE veterans' perceptions about research. MAIN METHODS: Transcribed discussions were content-analyzed. Participants discussed research-related motivators and barriers identified among other populations, and nuances that may be specific to GWE veterans. KEY FINDINGS: Examples of motivating factors included: seeking answers about causes of and treatment for health issues; helping oneself; and helping other veterans. Examples of barriers included: distrust and dissatisfaction with federal entities; lack of research follow-through; and concerns about privacy and confidentiality. SIGNIFICANCE: Researchers can use this information to better address GWE veterans' concerns and motivate them to participate in research. Inclusion of GWE veterans in research will allow researchers and clinicians to better understand and address health issues affecting this population.
Subject(s)
Focus Groups/methods , Gulf War , Interviews as Topic/methods , Patient Participation/methods , Qualitative Research , Veterans , Aged , Female , Focus Groups/standards , Humans , Interviews as Topic/standards , Male , Middle Aged , Motivation/physiology , Patient Acceptance of Health Care/psychology , Patient Participation/psychology , Pilot Projects , Veterans/psychologyABSTRACT
The US Department of Veterans Affairs (VA) Gulf War Era Cohort and Biorepository (GWECB) is a nationally representative longitudinal cohort of US veterans who served during the 1990-1991 Gulf War era. The GWECB combines survey data, such as demographic, health behavior, and environmental exposure data; medical records; and a linked biorepository of blood specimens that can support a broad range of future research regarding health concerns unique to veterans of this era. To build this resource, the VA Cooperative Studies Program initiated a pilot study (2014-2016) to establish the GWECB and evaluate the processes required to build and maintain the resource. Participants (n = 1,275) consented to future sharing of their data and biospecimens for research purposes. Here we describe the pilot study, including recruitment and enrollment procedures, data collection and management, quality control, and challenges experienced. The GWECB data available to investigators under approved sharing mechanisms and the procedures for accessing them are extensively detailed. The study's consenting documents and a website link for the research survey are provided. Our hope is that new research drawing on the GWECB data and biospecimens will result in effective treatments and improved approaches to address the health concerns of Gulf War-era veterans.
Subject(s)
Epidemiologic Methods , Gulf War , Health Status , Occupational Exposure/statistics & numerical data , Veterans/statistics & numerical data , Adult , Aged , Blood Specimen Collection , Environmental Exposure/statistics & numerical data , Female , Health Behavior , Health Surveys , Humans , Longitudinal Studies , Male , Middle Aged , Socioeconomic Factors , United StatesABSTRACT
The self-assembly of spherical magnets (magnetic balls) is addressed theoretically. Minimal energy structures are obtained by optimization procedures as well as Monte Carlo computer simulations. Three typical shapes are obtained depending on the number of constitutive magnets N. In the regime of small N, chains are stable as dimers or trimers (i.e., N≤3), then rings become stable for (4≤N≤13) where dipole vectors adopt a vortexlike arrangement. A major finding concerns the stacking of rings as soon as N is large enough (N≥14). The number of stacked rings is found to increase as N^{2/3}, leading to a tubular structure at large N. All the relevant predicted shapes are experimentally reproduced by manipulating millimetric magnets.
