Motion artifacts in capacitive ECG monitoring systems: a review of existing models and reduction techniques.

Current research focuses on improving electrocardiogram (ECG) monitoring systems to enable real-time and long-term usage, with a specific focus on facilitating remote monitoring of ECG data. This advancement is crucial for improving cardiovascular health by facilitating early detection and management of cardiovascular disease (CVD). To efficiently meet these demands, user-friendly and comfortable ECG sensors that surpass wet electrodes are essential. This has led to increased interest in ECG capacitive electrodes, which facilitate signal detection without requiring gel preparation or direct conductive contact with the body. This feature makes them suitable for wearables or integrated measurement devices. However, ongoing research is essential as the signals they measure often lack sufficient clinical accuracy due to susceptibility to interferences, particularly Motion Artifacts (MAs). While our primary focus is on studying MAs, we also address other limitations crucial for designing a high Signal-to-Noise Ratio (SNR) circuit and effectively mitigating MAs. The literature on the origins and models of MAs in capacitive electrodes is insufficient, which we aim to address alongside discussing mitigation methods. We bring attention to digital signal processing approaches, especially those using reference signals like Electrode-Tissue Impedance (ETI), as highly promising. Finally, we discuss its challenges, proposed solutions, and offer insights into future research directions.

Outcome of living kidney transplant: pediatric in comparison to adults.

BACKGROUND: Renal transplantation is the most optimal way to manage children with end-stage renal disease. Despite its benefits, pediatric renal transplantation is a challenge for several transplantation centers in terms of achieving a satisfactory outcome. We sought to compare the long-term outcome of pediatric versus adult recipients who underwent renal transplantation. METHOD: We examined, 2631 recipients of a first kidney from a living donor between 1982 and 2002. The two groups were matched for immunosuppressive therapy and number of HLA mismatches. The patients were divided into a pediatric (n=301; age 18 years) to compare 5-year patient and graft survivals. RESULTS: The mean ages of the pediatric and adult groups were 40 +/- 13 and 14 +/- 13 years, respectively. The 5-year graft survival was lower among the pediatric versus the adult group (56% vs 68%; P=.015) with no difference in patient survival (88% vs 86%; P>.05). CONCLUSION: The poorer graft survival in pediatric transplantation may be due to the nature of pediatric transplantation, in terms of inconsistent adherence to medication regimens, worse side effects of medications, higher rate of graft rejection due to recurrent disease, and more intense immunoreactivity of children.