1.
Eksp Klin Farmakol
; 63(5): 54-5, 2000.
Article
in Russian
| MEDLINE
| ID: mdl-11109529
ABSTRACT
The experiments on mice showed that 2-methyl-4-amino-hydroxypyrimidine (MAHP) exhibits a pronounced immunostimulant action upon the animal organism under extremal conditions. The effect of MAHP is related to the preferential activation of immunocompetent cells responsible for the immunity.
Subject(s)
Adjuvants, Immunologic/pharmacology , Pyrimidines/pharmacology , Stress, Psychological/immunology , Animals , Hemagglutinins/analysis , Immobilization , Male , Mice , Sheep , Swimming
2.
Eksp Klin Farmakol
; 63(4): 68-9, 2000.
Article
in Russian
| MEDLINE
| ID: mdl-11022313
ABSTRACT
Experiments on rats showed that some pyrimidine derivatives stimulate the skin repair in animals with thermal and chemical burns under stress conditions. The efficacy of compounds tested increases in the following order: 2-methyl-4-amino-6-hydroxypyrimidine < hydroxymethyluracil < methyluracil.