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1.
Pak J Pharm Sci ; 30(6): 2239-2245, 2017 Nov.
Article in English | MEDLINE | ID: mdl-29175795

ABSTRACT

In the present study the crude extracts of pollen of Centella asiatica (Linn.) Urban were explored for their antioxidant potential using Ferric Reducing Power, Metal Chelating Activity and Trolox Equivalent Antioxidant Capacity assays. In crude extracts of pollen antioxidant components were initially extracted in methanol and further fractionated in solvents of different polarity, such as n-Hexane, Chloroform, Ethyl Acetate and Water exhibited reasonable antioxidant activity. The extract was found to contain large amounts of phenolic and flavonoid contents ranged from 143-1155 mg/l of gallic acid equivalent (GAE) and 911-2488 mg/l of quercetin (QE) respectively. Moreover, Super oxide Anion Radical Scavenging Activity and GS-MS analysis were also carried out.


Subject(s)
Antioxidants/pharmacology , Centella/chemistry , Gas Chromatography-Mass Spectrometry , Iron Chelating Agents/pharmacology , Phytochemicals/pharmacology , Plant Extracts/pharmacology , Pollen/chemistry , Acetates/chemistry , Antioxidants/isolation & purification , Benzothiazoles/chemistry , Chlorides/chemistry , Chloroform/chemistry , Ferric Compounds/chemistry , Ferrous Compounds/chemistry , Hexanes/chemistry , Iron Chelating Agents/isolation & purification , Methanol/chemistry , Oxidation-Reduction , Phytochemicals/isolation & purification , Plant Extracts/isolation & purification , Plants, Medicinal , Solvents/chemistry , Sulfonic Acids/chemistry , Superoxides/chemistry , Water/chemistry
2.
Pak J Pharm Sci ; 27(2): 279-84, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24577915

ABSTRACT

Antioxidant potential of the pollen of Typha domigensis Pers. using Ferric Reducing ower, Metal Chelating Activity and Trolox Equivalent Antioxidant Capacity (TEAC) assays has been carried out in the current research work. The antioxidant components were initially extracted from the pollen in methanol and were further fractionated in solvents of different polarity such as n-Hexane, Chloroform, Ethyl Acetate and Water. Methanol extract which was found to have high reducing power, total phenolic contents with high metal chelating activity, has considerable prospective to utilize as a natural antioxidant and be capable to link with the total phenolic contents of plant.


Subject(s)
Antioxidants , Free Radical Scavengers , Plant Extracts/pharmacology , Pollen/chemistry , Typhaceae/chemistry , Algorithms , Benzothiazoles/chemistry , Chelating Agents/pharmacology , Ferric Compounds/chemistry , Flavonoids/analysis , Indicators and Reagents , Solvents , Sulfonic Acids/chemistry
3.
Acta Crystallogr Sect E Struct Rep Online ; 64(Pt 8): o1388, 2008 Jul 05.
Article in English | MEDLINE | ID: mdl-21203108

ABSTRACT

In the mol-ecule of the title compound, C(13)H(17)N(3)O, the two rings make a dihedral angle of 56.63 (13)°. Mol-ecules are linked by strong N-H⋯O inter-molecular hydrogen bonds into chains running along the c axis.

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