Abscisic acid and glycine betaine-mediated seed and root priming enhance seedling growth and antioxidative defense in wheat under drought.

The extent of drought tolerance in the seedlings of three wheat cultivars (WMRI-1, BARI GOM-33 and BARI GOM-21) was investigated by seed and root priming using abscisic acid (ABA) and glycine betaine (GB). The seeds were primed with ABA (10 and 20 µM) and GB (50 and 100 mM) and grown in pots maintaining control (0 % PEG) and drought (10 % PEG) conditions. Under drought, the root and shoot length, root and shoot biomass were significantly increased in ABA and GB primed seedlings than non-primed seedlings in all cultivars. Among the priming agents, either 20 µM ABA or 50 mM GB triggered better seedling growth in all wheat cultivars. These two levels were then applied with the nutrient solution in the hydroponics following four treatments: Control, Drought, Drought + ABA and Drought + GB. The seedling growth significantly declined in drought, while an improved seedling growth was observed in ABA and GB-treated plants in all cultivars. A considerable increase in lipid peroxidation, proline content, total antioxidant capacity and total flavonoid content in roots and leaves were recorded in all drought conditions, while these values were considerably reduced in ABA and GB treatments. Hierarchical clustering heatmap using stress tolerance index (STI) values showed that Drought + ABA and Drought + GB secured higher STI scores suggesting a greater degree of drought tolerance in all cultivars. In conclusion, seed and root priming of ABA and GB enhanced drought tolerance in the wheat seedlings by improving seedling growth and antioxidative defense suggesting a declined state of oxidative damage.

Pharmacological potentials of lycopene against aging and aging-related disorders: A review.

Aging and aging-related chronic disorders are one of the principal causes of death worldwide. The prevalence of these disorders is increasing gradually and globally. Considering this unwavering acceleration of the global burden, seeking alternatives to traditional medication to prevent the risk of aging disorders is needed. Among them, lycopene, a carotenoid, is abundant in many fruits and vegetables, including tomatoes, grapefruits, and watermelons, and it has a unique chemical structure to be a potent antioxidant compound. This nutraceutical also possesses several anti-aging actions, including combating aging biomarkers and ameliorating several chronic disorders. However, no systematic evaluation has yet been carried out that can comprehensively elucidate the effectiveness of lycopene in halting the course of aging and the emergence of chronic diseases linked to aging. This review, therefore, incorporates previous pre-clinical, clinical, and epidemiological studies on lycopene to understand its potency in treating aging disorders and its role as a mimic of caloric restriction. Lycopene-rich foods are found to prevent or attenuate aging disorders in various research. Based on the evidence, this review suggests the clinical application of lycopene to improve human health and alleviate the prevalence of aging and aging disorders.

Source-oriented risks apportionment of toxic metals in river sediments of Bangladesh: a national wide application of PMF model and pollution indices.

Intense human activities, particularly industrial and agricultural output, has enriched metal(loid)s in riverine sediment and endangered aquatic ecosystems and human health. Promoting proper river management requires an assessment of the possible ecological hazards and pollution posed by metal(loid)s in sediments. However, there are limited large-scale risk assessments of metal(loid)s contamination in riverine sediment in heavily populated nations like Bangladesh. This study compiled data on sediment metal(loid)s, for example, Cd, As, Cu, Ni, Cr, Pb, Mn, and Zn, from 24 major rivers located across Bangladesh between 2011 and 2022 and applied positive matrix factorization (PMF) to identify the critical metal(loid)s sources and PMF model-based ecological risks. Based on studied metal(loid)s, 12-78% of rivers posed higher contents than the upper continental crust and 8% of the river sediments for Cr and Ni, whereas 4% for Cd and As exceeded probable effect concentration. Cr and Ni in the sum of toxic units (STU), whereas Mn, As and Cd in potential ecological risk (PER) posed the highest contribution to contaminate sediments. In the studied rivers, sediment contaminant Mn derived from natural sources; Zn and Ni originated from mixed sources; Cr and Cu were released from the tannery and industrial emissions and Cd originated from agricultural practices. Source-based PER and NIRI indicated that mixed source (4% rivers) and tannery and industrial emission (4% rivers) posed very high risks in sediments. For the creation of macroscale policies and the restoration of contaminated rivers, our national-scale comprehensive study offers helpful references.

A review on toxic metal pollution and source-oriented risk apportionment in road dust of a highly polluted megacity in Bangladesh.

Heavy metal enrichment in road dust has resulted from intensive anthropogenic activity, particularly urbanization, industrial activities and traffic emission, posing a hazard to urban ecosystems and human health. To promote optimal road dust management in urban environments, it is necessary to assess the possible ecological and health impact of toxic elements in road dust. In a heavily populated megacity like Dhaka, Bangladesh, large-scale risk assessments of contamination in road dust with heavy metals are limited. The present study aims at presenting a concentration of twenty-five metals in road dust (Na, K, Cs, Rb, Mg, Ca, Sr, Ba, Al, Zn, Cd, Pb, As, Sb, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zr and W) in Dhaka megacity. We used a critical source-based positive matrix factorization model, source-oriented potential ecological risks and health risks. Out of the studied metals, Na, Ca, Zn, Cd, Cu, Zr and W exceeded the shale value. About 73%, 48%, 29% and 32% of sampling sites showed a higher level of pollution based on PLI, NIPI, PER and NIRI, respectively. PMF model identified that Cd (85.3%), Cr (62.4%), Ni (58.2%), Zn (81.8%) and Mn (65.9%) in road dust were primarily attributed to traffic emission, fuel combustion, metal processing, transport sources and natural sources, respectively. Fuel combustion and metal processing posed considerable and high risks based on modified potential ecological risk and NIRI. Based on health hazards, traffic emission posed a high cancer risk in adult males (29%), whereas transport sources contributed to females (21%) and children (23%).