Association Between Low Serum Magnesium Level And Type 2 Diabetes Mellitus In Abbottabad.

BACKGROUND: Magnesium serves as a cofactor for various oxidation reactions in the body and helps in glucose transport across cell membrane. Deficiency of magnesium is a common electrolyte abnormality in type 2 diabetic patients and is linked to development of various diabetic complications. This study was conducted to determine the association between low serum magnesium level and type 2 diabetes mellitus presenting at Medical B ward, BBS Hospital Abbottabad. METHODS: This descriptive study was conducted over a period of 6 months starting July 1, 2017. One hundred & eighty diagnosed diabetic patients aged at least 40 years, were included in the study. Their serum magnesium level was checked after withdrawing blood under strict aseptic conditions. Fasting & random blood glucose and the level of glycosylated haemoglobin were measured and age, gender, duration of illness were recorded on a proforma. RESULTS: Sixty-one patients (33.89%) had hypomagnesemia. There was no significant association between hypomagnesemia and age and sex of patients (p>0.05). However, hypomagnesemia was found to be significantly associated with the duration of diabetes mellitus among study population (p=0.02). CONCLUSIONS: Hypomagnesemia is frequently present in patients with diabetes mellitus and it appears that its prevalence increases with the duration of diabetes mellitus.

Pattern Of Leukaemia Patients Admitted In Ayub Teaching Hospital Abbottabad.

BACKGROUND: Any tissue of the body can give rise to cancer. However, those tissues which multiply rapidly are at high risk of developing cancer and haematopoietic system is one of them. Neoplasms of this system are known as leukaemia and lymphoma, according to the types of white cells involved. Study of cancer patterns in different societies, however can contribute a substantial knowledge about the aetiology of cancer. The present Study was designed and aimed to estimate the frequency of different types of leukaemia in patients admitted in Ayub Teaching hospital Abbottabad. METHODS: Data from the patients admitted at oncology Department of Ayub Teaching Hospital Abbottabad from 2010 to 2015 was collected and analysed to calculate cumulative and year-wise frequency of leukaemia and its major types. Frequency distribution with reference to gender and age was also calculated. RESULTS: In our analysis about 16% patients had acute myelocytic leukaemia and 32% patients had acute lymphocytic leukaemia; while chronic myeloid leukaemia outnumbered chronic lymphocytic leukaemia (11% and 3%); Hodgkin lymphoma was seen in 18% cases while Non Hodgkin lymphoma (NHL) was present in 20% cases. Out of the total, 150 cases (75%) belonged to mountainous areas of Hazara, i.e., 40 cases belonged to Kohistan, another 40 cases were residents of Battagram, 45 cases belonged to hilly areas of Mansehra and 25 cases to Kaghan valley, while only 50 (25%) cases were from the plain areas of Abbottabad and Haripur districts, i.e., 20 and 30 cases respectively. CONCLUSIONS: Leukaemia is more common in hilly areas of Hazara, since majority of the cases belonged to well-known mountainous regions of Kohistan, Battagram, Kaghan or Mansehra and only few cases belonged to the plain areas of Abbottabad and Haripur districts.

Nail mine in stomach.

Ingestion of foreign bodies is a common clinical scenario in any emergency department. Presence of thousands ingested foreign bodies inside stomach is a rare scene. However, only a few such cases have been reported. Here we present a case of young adult man with known psychiatric disorder, having 2562 nails in his stomach leading to gastric outlet obstruction. Gastrotomy was employed to relieve the stomach of this mine of nails. Later psychiatric care was also provided.

Correlation between plasma thyroid hormones and liver enzymes level in thyrotoxic cases and controls in Hazara Division.

BACKGROUND: Thyrotoxicosis is defined as increased synthesis and secretion of thyroid hormones; when associated with defused goitre it is known as grave's disease. Hepatic changes in thyrotoxiosis are fatty changes, cirrhosis and centrilobular necrosis, resulting in elevated serum levels of liver specific enzymes ALT, AST and ALK. Objective of the study was to determine a correlation between plasma levels of 3 liver enzymes, and thyroid hormones in thyrotoxic cases, and matched controls in Hazara Division. METHODS: This study was conducted at Ayub Teaching Hospital Abbottabad from 1st July 2004 to 30th June 2007. The controls were selected from staff and students of Ayub Medial College Abbottabad. Fifty cases of thyrotoxicosis and 50 controls were included in this study by convenience sampling. Their thyroid profile for T3, T4, TSH and liver enzymes profile for ALT, AST, ALK were determined and analysed for a correlation. RESULTS: Mean T3 of cases was 5.23 +/- 1.95 and of controls 1.95 +/- 0.35. Mean T4 of case was 248.88 +/- 62.75, and of controls was 113.40 +/- 19.01. Mean TSH of cases was 0.07 +/- 0.25 and that of controls was 2.24 +/- 0.80. Mean ALT of cases was 38.78 +/- 4.96 while that of controls was 23.98 +/- 5.27. Mean AST of cases was 39.76 +/- 5.05 and of controls was 26.52 +/- 4.49. Mean ALK of cases was 299.68 +/- 22.32 and of controls was 155.10 +/- 37.07. CONCLUSION: Although liver enzymes levels were slightly elevated in many thyrotoxic cases, no significant correlation emerged between any of the thyroid hormones and any of the liver enzymes, either in cases or controls.