ABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Granuloma/complications , Granuloma/diagnosis , Granuloma/drug therapy , Adrenal Cortex Hormones/therapeutic use , Betamethasone Valerate/therapeutic use , Mammography/methods , Cefuroxime/therapeutic use , Erythema/complications , Erythema/drug therapy , Breast Neoplasms , Diagnosis, Differential , Hidradenitis/complications , Hidradenitis/epidemiology , Lupus Vulgaris/complications , Acanthosis Nigricans/complications , Acanthosis Nigricans/pathologySubject(s)
Dermatitis/microbiology , Granuloma/microbiology , Tinea , Adult , Breast , Dermatitis/diagnosis , Female , Granuloma/diagnosis , Humans , Tinea/diagnosisSubject(s)
Lymphangioma/diagnosis , Vulva , Adult , Diagnosis, Differential , Female , Humans , Pregnancy , Pregnancy, Twin , Remission, SpontaneousABSTRACT
No disponible
Subject(s)
Child , Humans , Male , Amino Acids/therapeutic use , Hypopigmentation/drug therapy , Nail Diseases/congenital , Zinc Sulfate/therapeutic use , Nail Diseases/drug therapy , Remission Induction , Vitamins/therapeutic useSubject(s)
Foot Diseases/pathology , Leg , Nerve Sheath Neoplasms/pathology , Skin Neoplasms/pathology , Humans , Male , Middle AgedABSTRACT
Nine hundred and forty cases of breast lesions were subjected to fine needle aspiration. Nine hundred twenty-four of them were females and sixteen were males. Smears from the 60 female cases were rejected as unsatisfactory. Of the remaining 864 female cases (aged 15 to 72 years) 704 (81.4%) were benign. Histopathological correlations were done in 448 cases with diagnostic accuracy of 97.3%. One hundred and sixty (18.5%) out of 864 females were malignant and cytohistological correlation was done in 142 cases with 98.6% corroboration. Ten of the 16 male cases were histologically examined with full corroboration. Overall accuracy considering both males and females was 98.6%. Though there was underdiagnosis involving 12 cases of infiltrating ductal carcinoma when the lesions were small and deeply situated there was no overdiagnosis in this study.
Subject(s)
Breast Neoplasms/pathology , Developing Countries , Urban Population , Adolescent , Adult , Aged , Biopsy, Needle , Breast/pathology , Breast Diseases/epidemiology , Breast Diseases/pathology , Breast Neoplasms/epidemiology , Diagnosis, Differential , Female , Humans , India/epidemiology , Middle Aged , Urban Population/statistics & numerical dataABSTRACT
Fifty patients of acute renal failure following Viperine snake bite were studied. Oliguria (100%), local swelling (48%) and bleeding tendencies (42%) were the predominant clinical features encountered. Of the 25 patients in whom detailed coagulation studies were done, 24 patients had disseminated intravascular coagulation (DIC) and 1 had primary fibrinolysis. DIC was commoner with Russell's viper bite (62%) in comparison to Echis carinatus bites (40%). Renal histology obtained in 29 cases revealed tubular necrosis (35%), cortical necrosis (24%) tubular degeneration (17%) and glomerular changes (17%). Ballooning of glomerular capillaries (59%), splitting of glomerular basement membrane (40.7%), swelling of endothelial cells (29.6%), and focal proliferation of mesangial cells (17%) were the significant glomerular changes encountered. 20 (40%) patients succumbed, DIC (50%), irreversible shock (30%) and septicaemia (20%) being the immediate causes of death. Development of oliguria within 24 hours of snake bite and cortical necrosis were associated with higher mortality.
Subject(s)
Acute Kidney Injury/chemically induced , Viper Venoms/poisoning , Acute Kidney Injury/pathology , Adult , Female , Glomerular Mesangium/pathology , Humans , Kidney Tubular Necrosis, Acute/chemically induced , Kidney Tubular Necrosis, Acute/pathology , MaleABSTRACT
A wide spectrum of clinicopathological changes have been described in 50 cases of ARF following viperine snake bite studied prospectively over a 15-year period. Disseminated intravascular coagulation (DIC) was seen in 24/50 cases (Russel's viper bite in 62% and Ecchis carinatus bite in 42% of subjects). Histological examination of renal tissue obtained 1.5 days to 8 weeks after the bite revealed proliferative glomerular changes in 17 cases. These were characterized by ballooning of the capillaries, thickening and splitting of glomerular basement membrane (GMB), fibrin thrombi in the capillaries, and mesangial cell proliferation most prominently seen in Ecchis carinatus bites resulting in ARF.
Subject(s)
Acute Kidney Injury/etiology , Snake Bites/complications , Viper Venoms/poisoning , Acute Kidney Injury/pathology , Adolescent , Adult , Child , Disseminated Intravascular Coagulation/etiology , Disseminated Intravascular Coagulation/pathology , Female , Humans , India , Kidney Glomerulus/pathology , Kidney Tubules/pathology , Male , Prospective StudiesABSTRACT
A leprosy patient who developed acute renal failure on multidrug therapy is reported. The patient had initially received a once-weekly dose of rifampin and after he had stopped taking the drug for a time, was given rifampin on a once-monthly dose schedule. He recovered completely from his acute renal failure. Kidney biopsy showed interstitial nephritis with mononuclear and eosinophilic cellular infiltrates.
