ABSTRACT
Eighteen psoriasis patients were treated alternately with 40 mg of trioxalen and sunlight on the right side and sunlight only on the left side. Improvement was apparent faster on the psoralen-exposed side.
Subject(s)
Coumarins/therapeutic use , Photochemotherapy , Psoriasis/drug therapy , Sunlight , Trioxsalen/therapeutic use , Adolescent , Adult , Child , Female , Follow-Up Studies , Humans , Male , Middle AgedABSTRACT
Fifty-five patients with fixed drug eruption were investigated to determine the drug(s) causing the reaction. History, classic clinical features of well circumscribed erythema, edema and violaceous pigmentation, and the recurrence of the eruptions on the same sites on readministering drug were used as diagnostic criteria. This was confirmed by a provocative test. Sulfonamides and analgesics either alone or in combination were the most common causes of reaction.
Subject(s)
Drug Eruptions/etiology , Adolescent , Adult , Aged , Analgesics/adverse effects , Child , Child, Preschool , Drug Eruptions/diagnosis , Female , Humans , India , Male , Middle Aged , Recurrence , Sulfonamides/adverse effectsABSTRACT
A 5-year study of 668 patients with genital lesions revealed that teenagers and those in the age group of 20 to 40 are most vunerable. The poor, the uneducated and unmarried persons are at high risk. Chancroid and syphilis are the majority of cases. Inguinal bubo, herpes pregenitalis, condylomata acuminata, erosive balanitis and traumatic ulcers were seen less frequently. Most of the genital lesions had the classic clinical features. The findings of this study suggest that the pattern of genital lesions is showing borderline changes.
Subject(s)
Sexually Transmitted Diseases , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , India , Infant , Male , Middle Aged , Sexual Behavior , Sexually Transmitted Diseases/epidemiology , Socioeconomic FactorsABSTRACT
A review of 1,053 patients of leprosy revealed its prevalence in the hospital population as 2.4 per thousand. The commonly affected age group was 20-39 in both sexes; males predominating females in 1.8 : 1. The sequence of frequency of clinical types of leprosy was tuberculoid, borderline, neuritic and lepromatous. Mostly the patients report in the course of 2 years of awareness of the disease. The clinical features were classical and type specific.
Subject(s)
Leprosy/epidemiology , Adolescent , Adult , Age Factors , Aged , Child , Child, Preschool , Female , Humans , India , Infant , Infant, Newborn , Leprosy/complications , Leprosy/pathology , Male , Middle Aged , Sex FactorsABSTRACT
Vitiligo incidence in the series was 14 per thousand. The affliction of the younger subjects was frequent, the mean value of age at onset being 24.25 years. Both the sexes were affected and there was no significant difference between the two. The duration of the disease had wide variations, majority reporting in the course of one year. The emotional undertones and the ocurrence of the disease amongst family links were observed as provocating factors in some cases. Ivory white macules associated sometimes with erythematous tinge, leucotrichiae and islets of pigmentation were classic. The lower extremities were frequently involved, followed by face and other parts of the body. The disease was largely progressive, though in a few it was stationary. Vitiligo vulgaris was its commonest variant, followed by areata, zosteriformis, mucosae and acrofacialis. The associations namely diabetes mellitus, liver diseases and others were recorded. The occurrence of myasthenia gravis and trigeminal neuralgia in vitiligo was interesting. Its association on the basis of autoimmunity is brought out. The importance of the clinical parameters in anticipating the prognosis after psoralen therapy are discussed.
