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Article in Russian | MEDLINE | ID: mdl-7234260

ABSTRACT

Clinical examination of 83 patients with generalized herpes zoster has given the authors grounds to regard this disease as a result of activation of latent varicella-zoster virus. This assumption was confirmed by the results of indirect hemagglutination inhibition tests with 37 serum specimens taken from 18 patients. Treatment with antibiotics, the drug proper-myl, and by dehydration was the more effective, the earlier the patients were admitted to the clinic. Dehydration, proper-myl and combination of chloramphenicol with dehydration produced a more beneficial effect than the antibiotic alone. Five patients died. Problems of pathogenesis are discussed.


Subject(s)
Herpes Zoster/diagnosis , Adolescent , Adult , Age Factors , Aged , Biological Products/therapeutic use , Chloramphenicol/therapeutic use , Drug Combinations/therapeutic use , Drug Therapy, Combination , Female , Furosemide/therapeutic use , Herpes Zoster/epidemiology , Herpes Zoster/therapy , Humans , Male , Middle Aged , Penicillins/therapeutic use , Sex Factors , Yeast, Dried/therapeutic use
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