[Effectiveness of use in preventive nutrition the food ptoducts with contents of pectin and vitamins].

Daily inclusion in the diet of Pskov GRES workers the drinks or kissels containing 2 g pectin per daily serving (cup) during 6 months was accompanied by a statistically significant decline of their supply with vitamins C, B2, A and beta-carotene. This is reflected both in reducing the average vitamin concentration in blood serum and in the increase of the quota of people with deficiency of several vitamins. Additional inclusion of 13 vitamins in these drinks and kissels, in a dose about 80% of the RDA, has prevented the deterioration of vitamin status.

[Effect of vitamin beverages on vitamin sufficiency of the workers of Pskov Hydroelectric Power-Plant].

The research of influence of vitamin complexes in the form of a drink or kissel on vitamin sufficiency of working persons has been carried out. Long inclusion (6,5 months) in a diet of vitamin drinks containing about 80% from recommended daily consumption of vitamins, was accompanied by trustworthy improvement of vitamins C and B6 sufficiency and prevention of seasonal deterioration of beta-carotene status. As initially surveyed have been well provided with vitamins A and E, their blood serum level increase had not occurred.

[The influence of age and sex on fat- and water-soluble vitamins sufficiency of adulthood].

Serum concentrations of vitamins A, B2, B6, C, E and beta-carotene were determined in 174 healthy individuals ages 22-59 years. It was been shown that only 11% of examined men and 24% of women were well provided with all vitamins-antioxidants and beta-carotene. 38% cent of women and 67% cent of men had the combined insufficiency of 2-3 antioxidants (more often of vitamin C, B2 and beta-carotene). Men presented significantly higher serum retinol concentrations and lower concentrations of vitamin C and beta-carotene--than women. Serum concentrations of retinol for women and tocopherols for both men and women increased by 0.3% and 0.4% per year, respectively.

[Vitamin sufficiency of young basketball players]. / Obespechennost' vitaminami podrostkov-basketbolistov.

The investigation of vitamin sufficiency of young basket-ball players 14-16 years old (17 girls and 14 boys) has been carried out 59-77 per cent of the children had the deficiency of B group vitamins, 24-54 per cent--vitamin E insufficiency, most of them (82-100 per cent)--deficit of carotenoids while they were sufficiently vitamins C and A supplied. The girls were supplied with vitamins better than boys. There was no one adequately supplied with all vitamins among boys while 12 per cent of girls had adequately sufficiency. The girls had deficit of 1-2 vitamins more often whereas the combined insufficiency of 3-4 vitamins took place in 1.8-2.3 fold more frequently among boys. Daily intake of multivitamin containing 10 vitamins in daily recommended doses, lipoic acid, methionin and 9 minerals by boys lead to their blood plasma vitamin C, E, B-2 and beta-carotene level increase. Vitamin C insufficiency disappeared. Deficit of beta-carotene and vitamin B-6 became 1.5 fold rarely, vitamin B-2--2 fold, vitamin E--6 fold. Thus daily intake of recommended doses of vitamins eliminates biochemical signs of vitamin deficiency.

[Contents of vitamin C, E, B6, beta-carotene and food fibers in of mushrooms]. / Soderzhanie vitaminov C, E, B6, beta-Karotina i pishchevikh volokon v gribakh.

For specification and entering of the data in to Tables of a chemical compound of foodstuff definition of the content of vitamins C, E, B6 beta-carotene and dietary fibers in some kinds of the mushrooms collected in woods of Moscow suburbs was carried out. The received data testify to high enough content in them of vitamin C, especiale in white mushrooms and "fox" 24.0 and 28.8 mg%. The content of vitamin E in terms of a tocopherol-equivalent has made from 0.03 to 0.98 mg%.

[Vitamins stability in fortified dairy products]. / Sokhrannost' vitaminov v obogashchennykh molochnykh produktakh.

High safety of vitamins during vitaminization of dairy products has been shown. Adding of vitamins before pasteurization or sterilization of milk is guaranting its microbiological purity and doesn't change organoleptic quality of dairy products.

[The connection between vitamin and antioxidant status of the children with decreased hemoglobin level]. / Vzaimosviaz' mezhdu vitaminnym i antioksidantnym statusom u detei s ponizhennym urovnem gemoglobina.

The investigation of vitamin sufficiency of 96 children 4-15 years old living in Moscow with decreased hemoglobin level (less 120 g/l) has been carried out in spring in 2001. Most of the children (90 per cent) had the combined deficiency of B group vitamins and carotenoids while they were sufficiently vitamin C supplied. There were only 2 per cent of children adequately supplied with all vitamins. Range correlation between hemoglobin blood level and riboflavin and tocopherols serum concentration has been observed. Marked negative linear correlation between riboflavin and malone dialdehyde serum content has been revealed: more sufficiently supplied with vitamin B2 child has lower lipid oxidative product level. Thus the necessity of vitamin B2 including in complex therapy of iron deficiency is based.

[Vitamin sufficiency to preschool and young school age children from a group at risk for emergence of bone mineralization disorders]. / Obespechennost' vitaminami detei doshkol'nogo i mladshego shkol'nogo vozrasta iz gruppy riska po vozniknoveniiu narushenii mineralizatsii kostnoi tkani.

Vitamin status of 36 children 5-8 years old (Moscow) from the decreased bone mineral density risk group has been evaluated. Only 6-14 per cent of children had deep vitamin deficit. Vitamin B1 and B2 insufficiency has been observed 1.6 fold rarely among children additionally receiving vitamin supplement. The relation between urinary calcium and vitamins B1, B2 and B6 excretion has been shown. No difference was found in calcium excretion rate irrespective of additional vitamin intake. Although no correlation between urinary calcium/creatinine excretion and urinary vitamins C, B1, B2 and B6 excretion has been found children with increased calcium/creatinine index are insufficiently supplied with four vitamins more often. The data obtained could not be regarded as negation of the vitamin sufficiency importance for calcium metabolism and osteogenesis disturbance prevention.

[Use of the microalgae Spirulina platensis and its selenium-containing form in nutrition of patients with nonspecific ulcerative colitis]. / Ispol'zovanie mikrovodorosli spiruliny platensis i ee selensoderzhashcheé formy v pitanii bol'nykh nespetsificheskim iazvennym kolitom.

The vitamin security and selenium status were measured in the patients with unspecific ulcerative colitis. There were used food microalgae Spirulina platensis and it's preparation enriched with selenium as auxiliary tools of dietetic treatment for these patients. It's shown that there is a combined deficiency of beta-carotene and selenium and occasionally some other micronutrients in a significant part of the patients. The doses used of said food supplements were not enough sufficient for a dietary correction of deficiency of micronutrients with antioxidative properties.

[Use of multivitamin drink and oil solution of beta carotene in the treatment of children with chronic gastroduodenitis]. / Ispol'zovanie vitaminizirovannogo napitka i maslianogo rastvora beta-karotina v lechenii detei s khronicheskim gastroduodenitom.

Inclusion of vitamin-containing soft drink and oil solution of beta-carotene in the diet of the 4-14 years old children suffering from gastrointestinal diseases lead to vitamin and antioxidant status improvement with simultaneous positive effects on their clinical condition. Polyhypovitaminosis frequency had decreased. Thus, there is every reason to fortify diets of the patients suffering from gastrointestinal diseases with vitamins-antioxidants.

[Substantiation of the need of fortification with vitamins of the diet of children with gastrointestinal diseases]. / Obosnovanie neobkhodimosti obogashcheniia vitaminami ratsiona detei s zabolevaniiami zheludochno-kishechnogo trakta.

Surveys of 28 children have shown that 64 per cent of the children suffering from ulcerous disease of the stomach and the duodemun or chronic duodenitis have a combined deficiency of vitamin E, vitamins of the B group and beta-carotene. Diet No. 1 and No. 5 could not provide daily needs for vitamins. The patients were found to have a lower antioxidant activity of the blood serum, whereas the contents of hydroperoxides, double bonds and malonic dialdehydes were higher than in healthy children. The POL index in children with high beta-carotene deficiency was significantly higher than that in ailing children supplied with this carotenoid. Correlation analysis has revealed a reverse relationship between concentration of vitamin E and beta-carotene in blood serum and POL products, i.e. the better a child is supplied with these vitamins, the lower is the level of POL products. When the drink with the whole set of vitamins and an oil solution of beta-carotene was included in the diet of the children, it was found that hypovitaminosis frequency lowered with positive effects on their clinical condition and improved POL indexes. So there is a reason to fortify diets of children suffering from gastrointestinal disorders with vitamins-antioxidants.

[Effects of biologically active food additives with different contents of vitamins on the vitamin status in humans]. / Vliianie biologicheski aktivnykh dobavok k pishche s razlichnym soderzhaniem vitaminov na vitaminnyi status cheloveka.

The comparative study of influence of two biologically active food additives with the different contents of vitamins is carried out: a drink "Zolotoi Shar", the dose of vitamins in which makes 50-90% from recommended daily consumption, and "Vitabalance 2000", the contents of vitamins in which at 2-17 of time exceeds need of organism. The use of both additives within 3 weeks resulted in increase of levels of vitamins C, A, E, B2, B6 and carotenoids in blood serum. However if in case of consumption of a drink an authentic level was reached only for vitamin C and beta-carotene, in a case "Vitabalance 2000" for all investigated vitamins except vitamin A. Thus, if the consumption of a drink has lowered frequency of deficiency of 3-4 vitamins, but has not allowed to liquidate it completely, in case of "Vitabalance 2000" consumption the simultaneous deficiency 3-4 vitamins. The received data allow to believe the biologically active food additives containing vitamins in amounts exceeding recommended consumption, are convenient for fast liquidation of hypovitaminoses, and the preparations containing vitamins in doses making 30-50% from need of organism, are acceptable for daily filling of insufficient consumption of vitamins with a usual diet for a long time.

[Vitamin B 6 metabolism in phenylketonuria]. / Osobennosti obmena vitamina B-6 pri fenilketonurii.

Based on the analysis of the dependence of 4-pyridoxic acid urinary excretion from pyridoxal-5'-phosphate blood plasma level and its statistic distribution it has been shown that vitamin B-6 metabolism in children suffering from phenylketonuria and therefore the criteria of the body saturation with this vitamin differ from those for healthy people. Increased pyridoxal-5'-phosphate blood plasma level has been demonstrated for PKU children. The concentration of 11 ng/ml should be considered as a bottom border of the adequate supply with vitamin B-6. The elevated vitamin B-2 intake approximates vitamin B-6 status indexes of sick children to those usually measured in healthy children. The necessity for the reevaluation of vitamin B-2 and B-6 optimal diet content under this disease and its biochemical validation are discussed.

Effect of regular intake of vitamin-mineral complex on spontaneous and on induced clustogenesis in humans.

Regular intake of a vitamin-mineral complex for 2 weeks had no effect on spontaneous clustogenesis in blood cells from healthy donors. Significant differences between the levels of chromosome aberrations induced by bleomycin and dioxidine in vitro before and after 2-week vitamin treatment indicate increased resistance of blood cells to clustogens.

[Dependence of vitamin composition of breast milk on multivitamin intake during pregnancy and lactation]. / Zavisimost' vitaminnogo sostava grudnogo moloka ot priema polivitaminnykh preparatov v period beremennosti i laktatsii.

Investigation of vitamin status of 14 women 20-38 years of age has been carried out. All the women were adequately supplied with vitamins A and E. B group vitamins insufficiency among women receiving no vitamins during lactation takes place more often than among those who receive vitamins. Human breast milk vitamins content and percentage of women secreting enough milk quantity are higher in the group receiving vitamins. Thus, regular vitamins administration during pregnancy and lactation is necessary for milk vitamin content improvement.

[The effect of ftalazol on the body allowance in rats of B-group vitamins]. / Vliianie ftalazola na obespechennost' organizma krys nekotorymi vitaminami gruppy B.

A certain decrease in the content of riboflavin in blood plasma and liver and its excretion in the urine were encountered 24-h after administration of phthalazol, according to the schedule of acute dysentery treatment, in rats with initial moderate deficiency in vitamins B1 and B2. The provision with vitamin B1 did not change in this case. The introduction of phthalazol was attended with a noticeable decrease in the excretion of pyridoxic acid but did not affect the B6 content in the liver and blood serum of the animals.

[Seasonal variations of vitamin sufficiency in pregnant women (Mzensk City)]. / Sezonnye razlichiia v obespechennosti vitaminami beremennykh (g. Mtsensk).

The investigation of sufficiency of vitamin C, A, E, B2, B6, carotenoids and iron dietary intake has been carried out in 61 pregnant women in spring and early autumn 1998. There were no women adequately supplied with all vitamins irrespective of season and residence. Most of them (70-80 per cent) had combined deficiency of 3-5 vitamins in spring. About 50 per cent of women had combined insufficiency of vitamins and iron. Intake of vitamins improved in autumn especially due to vitamins C, A, E and carotenoids. The frequency of 3-5 vitamins deficit decreased while occurrence of combined deficiency of vitamin B6 and carotenoids still often took place. Thus, normalization of vitamin status of pregnant women is necessary all year round.

[Comparative study of special products "Tetraphen" and "Phenyl-free" in diet therapy of children with phenylketonuria]. / Sravnitel'naia otsenka ispol'zovaniia spetsializirovannykh produktov "Tetrafen" i "Fenil-fri" v dietoterapii detei, bol'nykh fenilketonuriei.

Basing on the comparative clinical and biochemical evaluation of the usage of the specialized product "Tetraphen" (Russia) and early utilized product "Phenyl-Free" (USA) it has been shown that "Tetraphen" does not yield to "Phenyl-Free", while some of its parameters (energy value, carbohydrate content) even in the higher degree correspond to the physiologic requirements of this aged children suffering from phenylketonuria. Intake of this product in smaller doses completely covers their requirements for the basic food ingredients. High frequency of carotenoids insufficiency in children received both "Tetraphen" and "Phenyl-Free" demonstrate necessity of the diet correction by means of beta-carotene additional supplementation.

[Influence of lead on metabolism of vitamins B group in alimentary iron deficient rats]. / Vliianie svintsa na obmen vitaminov gruppy B pri alimentarnoí nedostatochnosti zheleza u krys.

Experimentally induced lead poisoning especially under simultaneous iron deficit leads to the development of secondary thiamine insufficiency. Erythrocyte riboflavin content and erythrocyte glutathion reductase and aspartate aminotransferase activities have been demonstrated to be increased. Lead treatment is accompanied with the increase of urinary excretion of riboflavin, 4-pyridoxic acid and 1-vtthylnicotinamide in rats fed with adequate diet. Thus lead intoxication and iron deficiency influence vitamin B group metabolism.

[Study of the relationship between indicators of provision with vitamins B2 and B6 of children 7-10 years of age with mental retardation]. / Izuchenie vzaimosviazi mezhdu pokazateliami obespechennosti vitaminami B2 i B6 detei 7-10 let s zaderzhkoi psikhicheskogo razvitiia.

Study of the vitamin status of 34 children of both sexes aged 7 to 10, pupils of a school for children with mental retardation in the city of Krasnoyarsk revealed that the values of riboflavin and 4-pyridoxic acid excretion per g of creatinine, which are in good correlation with the content of the respective vitamins in the blood, reflect the saturation with these nutrients and may be used for assessing vitamin supply. Excretion of at least 200 mg of riboflavin per g of creatinine corresponds to normal provision of a child with this vitamin.