ABSTRACT
We report a case of 15 year old female patient of xeroderma pigmentosum with large squamous cell carcinoma on the left side of cheek. She received combination chemotherapy with isotretinoin for a period of 4 months and showed complete clinical remission of tumour. The role of isotretinoin in cancer prevention and management of malignancies associated in xeroderma pigmentosum is also reviewed through literature.
Subject(s)
Antineoplastic Agents/therapeutic use , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/drug therapy , Dermatologic Agents/therapeutic use , Facial Neoplasms/drug therapy , Head and Neck Neoplasms/complications , Head and Neck Neoplasms/drug therapy , Isotretinoin/therapeutic use , Xeroderma Pigmentosum/drug therapy , Adolescent , Antimetabolites, Antineoplastic/administration & dosage , Antineoplastic Agents/administration & dosage , Cisplatin/administration & dosage , Facial Neoplasms/complications , Female , Fluorouracil/administration & dosage , Humans , Isotretinoin/administration & dosage , Squamous Cell Carcinoma of Head and Neck , Xeroderma Pigmentosum/complicationsSubject(s)
Breast Neoplasms, Male/pathology , Lymphoma/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Breast Neoplasms, Male/diagnostic imaging , Breast Neoplasms, Male/drug therapy , Gynecomastia/diagnosis , Humans , Lymphoma/diagnostic imaging , Lymphoma/drug therapy , Male , Mammography , Middle Aged , UltrasonographyABSTRACT
Incidence of thyroidal masses is very high with predominance in females. Most of these masses are benign. Malignancy can be of thyroid or non-thyroid origin. Surgery is treatment of choice in the former but not in latter. Primary thyroid lymphoma (PTL) is a rare cause of thyroid malignancy of non-thyroid origin which is highly treatable without surgery but early diagnosis is important requisite to have better outcome. Fine needle aspiration cytology (FNAC) is an important tool in early diagnosis of PTL, which enables doctors to treat patient better without major surgery and its morbidity. Two cases of primary thyroid lymphoma are hereby presented. The patient diagnosed on FNAC had better outcome than the one who had major surgery.
