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Biokhimiia ; 50(11): 1853-8, 1985 Nov.
Article in Russian | MEDLINE | ID: mdl-4063405

ABSTRACT

Equilibrium binding of labeled estron, estradiol, estriol and DES was studied in uterine cytosol of immature Wistar rats. The dissociation kinetics of the ligand complexes with specific high affinity sites suggested the homogeneity of estrogen receptors in rat uterine cytosol. The feasibility of intracellular regulation of estrogen action in target cells both at the receptor and post-receptor levels is discussed.


Subject(s)
Estrogens/metabolism , Receptors, Estrogen/metabolism , Uterus/metabolism , Animals , Cytosol/metabolism , Estradiol/metabolism , Estriol/metabolism , Estrone/metabolism , Female , In Vitro Techniques , Kinetics , Rats , Rats, Inbred Strains
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