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Biull Eksp Biol Med ; 113(3): 304-6, 1992 Mar.
Article in Russian | MEDLINE | ID: mdl-1421235

ABSTRACT

The existence of the antigen associated with human cervical squamous cell cancer in normal and pathologically changed cervical epithelium was studied. Immunocytochemical and immunohistochemical methods were used. It is shown that the levels of the antigen increase significantly as the severity of dysplastic changes in epithelial stratum grows and tumor invasive growth begins. The data obtained indicate that the above tumor-associated marker can be useful in the follow-up for prognosticating a course of cervical cancer and dysplasia.


Subject(s)
Antigens, Neoplasm/analysis , Biomarkers, Tumor , Carcinoma, Squamous Cell/immunology , Uterine Cervical Neoplasms/immunology , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/pathology , Diagnosis, Differential , Female , Humans , Immunohistochemistry , Prognosis , Uterine Cervical Dysplasia/diagnosis , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/pathology
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