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Angiol Sosud Khir ; 21(3): 83-4, 86-9, 2015.
Article in Russian | MEDLINE | ID: mdl-26355926

ABSTRACT

Widely incorporated into vascular surgery pharmacological thrombolysis in treatment for deep vain thrombosis is fraught with a series of unsolved problems requiring further consideration. In spite of aggressive nature of treatment in a series of cases pharmacological thrombolysis sometimes turns out ineffective. Along with it, the results of experimental studies suggest a possibility of accelerating resorption of thrombotic masses and inhibiting remodelling of the venous wall by means of influencing effector cells of endogenous thrombolysis. A detailed study of the mechanisms of thrombolysis would make it possible to formulate strict criteria for carrying out pharmacological thrombolysis and to increase its efficacy.


Subject(s)
Antithrombins , Catheterization, Peripheral/methods , Fibrinolysis , Thrombolytic Therapy/methods , Venous Thrombosis , Antithrombins/metabolism , Antithrombins/pharmacology , Combined Modality Therapy , Fibrin/metabolism , Humans , Outcome Assessment, Health Care , Venous Thrombosis/drug therapy , Venous Thrombosis/metabolism , Venous Thrombosis/surgery
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