Chronic histiocytic intervillositis (CHI): an under-recognised condition with potential serious sequelae in pregnancy.

Chronic histiocytic intervillositis (CHI) is a rare placental disorder associated with adverse pregnancy outcomes and high recurrence rates in subsequent pregnancies. We discuss a case of CHI diagnosed incidentally in a young primigravida who presented with a first trimester miscarriage. CHI is usually diagnosed after an adverse pregnancy outcome by microscopic placental histopathology. Currently, CHI is a poorly understood condition by clinicians in many aspects, including its aetiology and subsequent management of patients in their future pregnancies. This is due to the lack of awareness and underdiagnosis of CHI among general pathologists and obstetricians. The authors would like to highlight this interesting case to encourage more research on CHI to understand its pathophysiology and optimal management better. Clinicians should also focus on providing holistic care to this group of patients by considering the impact of adverse pregnancy outcomes on their emotional well-being.

Rare malignant peripheral nerve sheath tumour of the endocervix masquerading as a leiomyoma.

•MPNST arising from a gynaecological origin is rare.•It poses a diagnostic challenge with symptoms and imaging - histology is essential.•Current mainstay of treatment involves radical surgery with clear margins.•The benefits of chemotherapy and radiotherapy are not well established.

Unusual case of a small bowel leiomyoma presenting as an adnexal mass.

This case report will discuss an interesting case of a premenopausal woman who presented with an adnexal mass consistent with a leiomyoma on imaging. However, intraoperatively, the mass was thought to be a gastrointestinal stromal tumour but histological diagnosis subsequently confirmed a leiomyoma arising from the small bowel.

Uterine artery embolisation for acute dysfunctional uterine bleeding with failed medical therapy: a novel approach to management.

A 35-year-old woman with a history of three previous caesarean sections was admitted with acute dysfunctional uterine bleeding (DUB) complicated by anaemia; she had a haemoglobin level of 5.3 g/dL, requiring multiple blood transfusions. Investigations performed excluded pelvic pathology and haematological causes for her acute DUB. Despite the use of various pharmacological agents, her bleeding persisted and she eventually underwent uterine artery embolisation (UAE) to arrest bleeding. She was well postprocedure and was discharged on combined oral contraceptives. However, she presented a year later with another episode of acute DUB that required a repeat UAE. This case report summarises the use of UAE in the management of acute DUB following failed medical therapy.