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2.
J Chem Phys ; 157(5): 054304, 2022 Aug 07.
Article in English | MEDLINE | ID: mdl-35933194

ABSTRACT

It has recently been shown that an interferometric approach can be used to obtain Auger lifetimes in molecules in certain point groups. Here, we extend this concept to those molecular states for which Auger decay is energetically forbidden and which exhibit initial quasi-exponential decay followed by quantum revivals. We demonstrate that this allows us to extract the quasi-exponential decay rate and the revival timescale. We solve analytically a model containing a state coupled to the idealized Bixon-Jortner quasicontinuum, and we obtain an interferometric signature of revival, which can be easily generalized to realistic systems. Moreover, we analyze how this revival signature is influenced by the system parameters, and we suggest optimal conditions for its observation. We, therefore, show that our new approach allows population revivals of a molecular state to be detected interferometrically.

3.
Opt Express ; 29(4): 5982-5992, 2021 Feb 15.
Article in English | MEDLINE | ID: mdl-33726129

ABSTRACT

Extreme ultraviolet (XUV) radiation finds numerous applications in spectroscopy. When the XUV light is generated via high-order harmonic generation (HHG), it may be produced in the form of attosecond pulses, allowing access to unprecedented ultrafast phenomena. However, the HHG efficiency remains limited. Here we present an observation of a new regime of coherent XUV emission which has a potential to provide higher XUV intensity, vital for applications. We explain the process by high-order parametric generation, involving the combined emission of THz and XUV photons, where the phase matching is very robust against ionization. This introduces a way to use higher-energy driving pulses, thus generating more XUV photons.

4.
Phys Rev Lett ; 122(23): 233001, 2019 Jun 14.
Article in English | MEDLINE | ID: mdl-31298870

ABSTRACT

We introduce and present a theory of interferometric measurement of a normal Auger decay lifetime in molecules. Molecular Auger interferometry is based on the coherent phase control of Auger dynamics in a two-color (ω/2ω) laser field. We show that, in contrast to atoms, in oriented molecules of certain point groups the relative ω/2ω phase modulates the total ionization yield. A simple analytical formula is derived for the extraction of the lifetimes of Auger-active states from a molecular Auger interferogram, circumventing the need in either high-resolution or attosecond spectroscopy. We demonstrate the principle of the interferometric Auger lifetime measurement using inner-valence decay in CH_{3}F.

5.
J Phys Condens Matter ; 31(3): 033001, 2019 01 23.
Article in English | MEDLINE | ID: mdl-30523972

ABSTRACT

Growth and survival of biological cells (eukaryotes and prokaryotes) on artificial environments often depend on their interactions with the specific surface. Various organic materials can be coated on substrates to assist cells' adhesion and other subsequent cellular processes. However, these coatings are expensive, degrade over short time period, and may even interfere with the cells' signaling processes. Therefore, the use of inorganic surfaces in order to control cellular interactions is of scientific importance from fundamental and application perspectives. Among inorganic materials, oxide thin films have received considerable attention. Thin films of oxides have the advantage of tailoring the surfaces for cellular interactions while using a negligible amount of the oxide material. Here, we review the lesser known application of inorganic oxide coatings as biocompatible and implantable platforms for different purposes, such as biofilm inhibition, cell culture and implant enhancements.


Subject(s)
Coated Materials, Biocompatible/chemistry , Oxides/chemistry , Oxides/pharmacology , Animals , Coated Materials, Biocompatible/pharmacology , Humans
6.
Article in Russian | MEDLINE | ID: mdl-30499486

ABSTRACT

BACKGROUND: Physical overload results in the development of pathological changes in the organs and systems and thereby causes their dysfunction. This leads to disadaptation, vegetative imbalance, and disturbances in the cardiovascular, nervous, endocrine and other systems. Taken together, these changes give rise to a syndrome of overtraining. In this context, the pathogenetically sound method of therapy appears to be the most suitable for the management of this condition based on the physiotherapeutic non-invasive interventions for the correction of physiological characteristics and the psycho-emotional status of the patients. One such method is bioresonance therapy (BRT). AIM: The objective of the present study was to evaluate the influence of bioresonance therapy (BRT) on the health status of the athletes presenting with the overtraining syndrome. MATERIAL AND METHODS: The study included 60 athletes presenting with the overtraining syndrome. They were divided into two groups each comprised of 30 subjects of comparable age, sex, sport, and sports qualification. Group I was composed of 30 athletes who were treated by means of bioresonance therapy. Group II (control) contained the athletes who received placebo procedures (i.e. the procedures with the use of a non-functioning device). All the athletes were examined before and after the treatment with the application of the clinical and instrumental methods. RESULTS: The study has demonstrated that the use of bioresonance therapy significantly increases the parasympathetic influence on the rhythm of the heart, reduces the stress on the central contour of its regulation, contributes to the 'economization' of the cardiac activity; has an antihypertensive effect (more pronounced with respect to systolic blood pressure (SBP)), has a normalizing effect on the variability of blood pressure (BP) in the patients with initial BP instability, and significantly decreases the time index in connection with monitoring blood pressure; moreover, BRT has a normalizing effect on the circadian rhythm of BP and corrects the rate of the morning rise in diastolic blood pressure (DBP). CONCLUSION: Bioresonance therapy can be considered as a method for the correction of the syndrome of overtraining in the athletes with the enhanced activity of the sympathetic nervous system.


Subject(s)
Athletes , Bioresonance Therapy , Physical Endurance/physiology , Blood Pressure/physiology , Female , Humans , Male , Sports , Syndrome , Treatment Outcome
7.
Opt Express ; 26(12): 15745-15758, 2018 Jun 11.
Article in English | MEDLINE | ID: mdl-30114831

ABSTRACT

We have studied high-order harmonic generation (HHG) in an indium ablation plume driven by intense few-cycle laser pulses centered at 775 nm as a function of the frequency chirp of the laser pulse. We found experimentally that resonant emission lines between 19.7 eV and 22.3 eV (close to the 13th and 15th harmonic of the laser) exhibit a strong, asymmetric chirp dependence, with pronounced intensity modulations. The chirp dependence is reproduced by our numerical time-dependent Schrödinger equation simulations of a resonant HHG by the model indium ion. As demonstrated with our separate simulations of HHG within the strong field approximation, the resonance can be understood in terms of the chirp-dependent HHG photon energy coinciding with the energy of an autoionizing state to ground state transition with high oscillator strength. This supports the validity of the general theory of resonant four-step HHG in the few-cycle limit.

8.
Arkh Patol ; 54(4): 20-4, 1992.
Article in Russian | MEDLINE | ID: mdl-1444850

ABSTRACT

The morphological features of chronic myeloid leukemia at different stages of the disease were specified basing on the study of bone marrow punch biopsies of 239 patients, surgically removed spleens of 32 patients, marginal liver biopsies of 22 patients and 69 autopsies. It was found valid to distinguish two histological variants: granulocytic and granulocytic-megakaryocytic. It was shown that in the latter form of leukemia myelofibrosis, primarily of reticulin type, often tends to develop. The granulocytic-megakaryocytic variant and the diffuse myelofibrosis were found to be related to the morphological manifestations of unfavourable prognosis of chronic myeloid leukemia. The accumulation of blast cells in the central parts of bone marrow cavities, as revealed in the punch biopsies is the indication of the beginning of the blast transformation.


Subject(s)
Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology , Biopsy , Blast Crisis/pathology , Bone Marrow Examination/methods , Humans , Prognosis
12.
Arkh Patol ; 50(5): 53-8, 1988.
Article in Russian | MEDLINE | ID: mdl-3415512

ABSTRACT

Posttransfusion and postinfusion side effects and complications resulting occasionally in lethal outcomes are still available in clinical practice in spite of apparent safety and high efficiency of blood transfusions and infusions. These may be caused by the donor-recipient erythrocytic incompatibility, poor quality of the transfusion medium, disregard of contraindications to transfusion. Pathologic features of complications emerging in response to transfusion of incompatible blood or its substitutes are indicated as well as morphologic characteristics specific for posttransfusion shock and consequent acute hepatorenal insufficiency. For the substitutes there are occasional observations of the shock similar in its development to an anaphylactic one. Wide introduction of transfusion and infusion therapy into clinical practice dictates the necessity of adequate evaluation of the above therapy role in combined treatment of varying-type patients, in thanatogenesis basing on the initial patient status and previous treatment.


Subject(s)
Iatrogenic Disease , Infusions, Parenteral/adverse effects , Transfusion Reaction , Autopsy , Blood Transfusion/mortality , Cause of Death , Humans , Infusions, Parenteral/mortality , Kidney/pathology , Liver/pathology , Moscow
16.
Arkh Patol ; 48(7): 43-7, 1986.
Article in Russian | MEDLINE | ID: mdl-2428336

ABSTRACT

Rats and rabbits were infused with solutions of hydroxyethyl starch (HES) with different physical and chemical properties. Large quantities of HES produced specific macrophage reaction in the spleen. When used in therapeutic doses (plasmaexpander) HES caused no macrophage reaction. HES proved to be non-toxic for the internal organs.


Subject(s)
Hydroxyethyl Starch Derivatives/toxicity , Starch/analogs & derivatives , Animals , Chemical Phenomena , Chemistry, Physical , Dose-Response Relationship, Drug , Infusions, Parenteral , Macrophages/drug effects , Macrophages/pathology , Rabbits , Rats , Solutions , Spleen/drug effects , Spleen/pathology , Time Factors
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