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Georgian Med News ; (250): 72-5, 2016 Jan.
Article in Russian | MEDLINE | ID: mdl-26870979

ABSTRACT

Ceftriaxone is a third generation cephalosporin antibiotic and is one of the most often applicable parenteral drug, which has wide antimicrobial activity range. According to the literature gall bladder lithiasis is a complication which is described in the first days of the treatment with this antibiotic. The cases are seen mostly as undergdiagnosed conditions when ultrasound examination is performed due to the abdominal colics. The aim of the study was to observe Cholelithiasis in ceftriaxone-treated patients. Last year few cases of Cholelithiasis were observed in Children's Infectious Diseases Hospital. All of them were related to the dysentery treatment with ceftriaxone. All of the cases of Cholelithiasis were diagnosed at the beginning of the antibiotic therapy (in first 2-3 days of hospitalization). Gall bladder concernments/sludge were found accidentally. Cholelithiasis in these cases was transitory and in 2 weeks ultrasound investigation revealed no calculi/sludge in the gall bladder. Further findings are supposed to be analyzed on a bigger number of the patients. It is necessary to follow up with gall bladder concernments till their absolute resolution.


Subject(s)
Anti-Bacterial Agents/adverse effects , Bacterial Infections/drug therapy , Ceftriaxone/adverse effects , Cholecystolithiasis/chemically induced , Dysentery/drug therapy , Gallbladder Diseases/chemically induced , Child, Preschool , Female , Humans , Infant , Male
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