[Significance of radioimmunologic studies in the diagnosis, assessment of severity and prognosis of myocardial infarct]. / Znachenie radioimmunologicheskikh issledovanii v diagnostike, otsenke tiazhesti i prognoza infarkta miokarda.

The authors presented the results of a radioimmunoassay of myoglobin (MG), MV-fraction of creatine phosphokinase (CPK), hypophyseal thyrotropic hormone, peripheral thyroid hormones and testosterone in 150 patients with acute myocardial infarction. A high informative value of the radioimmunoassay was shown. The MG level and MV-CPK activity as well as the functioning of the hypophyseal-thyroid system were shown to be directly correlated with the severity of disease and were of prognostic value. A considerable suppression of hypophyseal and thyroid function coinciding with the maximum values of myoglobinemia in the most severe cases was noted. Three variants of the testosterone content were singled out in patients with acute myocardial infarction. Paroxysmal rhythm disorders in the 1st variant (up to 300 ng/100 ml) and A-V blockades (over 1000 ng/100 ml) in the 3rd variant were frequently noted.