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1.
Curr Probl Cardiol ; 46(3): 100743, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33280894

ABSTRACT

Trigger factors such as earthquakes, war, and terrorism have been shown to increase the risk of cardiovascular events in different studies. Similarly, strong emotions and psychological stress have been associated with myocardial infarction, symptomatic arrhythmias, and sudden cardiac death. Die-hard soccer, rugby, football, and baseball fans seem to be at risk of cardiac events, particularly in individuals with prior history of coronary artery disease. Transient hemodynamic changes, endothelial dysfunction, and an overwhelming sympathetic nervous system stimulation appear to affect cardiac hemostasis creating a procoagulant and arrhythmogenic environment. High-risk behaviors such as tobacco abuse and binge drinking appear to contribute to this risk generating a proinflammatory state characterized by elevated levels of endothelin-1 and overexpression of sCD40L, sVCAM-1, MCP-1, and TNF-alpha. The outcome of the game and unexpected results, especially among fans of the defeated team, seem to further correlate with adverse cardiovascular effects.


Subject(s)
Arrhythmias, Cardiac , Death, Sudden, Cardiac , Sports , Humans , Death, Sudden, Cardiac/epidemiology , Death, Sudden, Cardiac/etiology , Football , Soccer , Stress, Psychological , Rugby , Baseball
2.
Curr Probl Cardiol ; 46(3): 100718, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33097299

ABSTRACT

Omega-3-fatty-acids are now increasingly being used for potential beneficial anti-inflammatory effect in the treatment and management of cardiovascular disease. Eicosapentaenoic acid and Docosahexaenoic acid are 2 essential omega-3 fatty acids found predominately in fish and fish oil supplements. Despite the increased use of fish oil products for both primary and secondary prevention of cardiovascular morbidity and mortality, the available literature evidence are controversial. We searched through PubMed for studies that have investigated the impact of omega-3 fatty acids on coronary heart disease and mortality. Our systemic review suggests that most studies, which are mostly observational, have found there to be a potential benefit of omega-3 fatty acids on coronary heart disease whereas some other studies have found conflicting results. More randomized controlled studies are warranted with adequate sample size to clearly establish the risk and benefits of omega-3 fatty acids on cardiovascular disease.


Subject(s)
Arrhythmias, Cardiac , Cardiovascular Diseases , Fatty Acids, Omega-3 , Arrhythmias, Cardiac/epidemiology , Arrhythmias, Cardiac/prevention & control , Cardiovascular Diseases/etiology , Cardiovascular Diseases/prevention & control , Docosahexaenoic Acids/administration & dosage , Docosahexaenoic Acids/adverse effects , Eicosapentaenoic Acid/administration & dosage , Eicosapentaenoic Acid/adverse effects , Fatty Acids, Omega-3/administration & dosage , Fatty Acids, Omega-3/adverse effects , Fish Oils/therapeutic use , Humans , Randomized Controlled Trials as Topic , Secondary Prevention
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