[The use of the preparation defedrin in the therapy of bronchial asthma patients]. / Prilozhenie na preparata defedrin v terapiiata na bolni ot bronkhialna astma.

The therapeutic efficacy of the Soviet drug Dephedrin was tried in patients with mild and moderate form of bronchial asthma. The drug was administered in a dose of 0.03 g 3 times daily for a period of 15 days. Out of 10 patients with mild form of bronchial asthma in patients the effect was very good, in 5 patients it was good and in patient it was poor. Out of 10 patients with moderate form of bronchial asthma in 3 patients the effect was very good, in 3 patients it was good and in 4 patients--poor. The ventilation indices improved but without reacting statistical significance. The conclusion is that Dephedrin is suitable for the mild form of bronchial asthma.

[Androstenedione, DHEA sulfate, cortisol, aldosterone and testosterone in bronchial asthma patients]. / Androstendion, DKhEA-sulfat, kortizol, aldosteron i testosteron pri bolni ot bronkhialna astma.

The basic level and the 24 h rhythm of secretion of cortisol, aldosterone, androstanedion, DHEA-sulfate and testosterone were determined in 26 men with bronchial asthma, 19 up to 50 years of age, in a free from attacks period. 20 of the patients had never been treated with corticosteroids and 6 patients had used corticosteroid drugs. In 26.32% of the patients who had not been treated with corticosteroids the basic cortisole level was either decreased or on the lower normal limit. At the same time in 55% of these patients a different degree increase of the basic DHEA-sulfate level was found and in 30% of the patients the androstanedione basic level was increased. The changes in the 24 h rhythm of androstanedione and DHEA-sulfate secretion were similar to those of cortisol. Normal rhythm of secretion of cortisol, aldosterone and testosterone was established mainly in patients with preserved basic hormonal secretion. In contrast to these, normal rhythm of androstanedione and DHEA-sulfate secretion was found more frequently in patients with increased basic secretion of these hormones.

[Multicausality in the pathology of commercial swine breeding]. / Multikauzalnost v patologiiata na promishlenoto svinevudstvo.

Studied were more than 100,000 samples of pathologic tissue material, 1,900 whole blood and blood serum samples, 8,000 fecal samples, 2,600 washings samples, swab samples, and other sampled material via the employment of a number of bacteriologic, virologic, morphologic, hematologic, biochemical, parasitologic, and other routinely applicable laboratory methods over a period of 5 years. All materials were taken from 15 stock swine breeding complexes, 3 reproduction and 2 nucleus bases for hybrid pigs, and 3 swine breeding farms with a practice of extensive raising technology. It was demonstrated that the adaptive capacity of the animals of the Camborough hybrid sharply dropped when the pigs were kept under unconventional conditions of raising, leading to deviations in the application of industrial technology methods. This was the reason to observe the simultaneous manifestation of conditionally substantiated disease outbreaks (multiple causality), with great economic losses. Studied were the etiology and pathogenesis of coli bacteriosis, salmonellosis, gastric ulcer, hypotrophy, atrophic rhinitis, geohelminthiases, chlamydial infections, and erysipelas. Suggested is the use of programmes and methods of prophylaxis and treatment, of expedient diagnosis and control on immunity.