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Bull Exp Biol Med ; 145(6): 680-1, 2008 Jun.
Article in English | MEDLINE | ID: mdl-19110549

ABSTRACT

We studied enzyme systems (lactate dehydrogenase) of mitochondria in cerebral nerve cells in experimental encephalopathy developing after thermal injury. In animals receiving neuromedin at the early terms after injury, the ratio of forward to reverse lactate dehydrogenase reactions significantly increased over the first day after injury and returned to normal on day 7.


Subject(s)
Aminoquinolines/pharmacology , Brain Injuries/enzymology , Burns/enzymology , L-Lactate Dehydrogenase/metabolism , Mitochondria/drug effects , Animals , Brain Injuries/physiopathology , Burns/physiopathology , Enzyme Activation/drug effects , Male , Mitochondria/enzymology , Rats , Rats, Wistar
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