Subject(s)
Cetirizine , Kimura Disease , Acetates/therapeutic use , Cetirizine/therapeutic use , Child , Cyclopropanes , Double-Blind Method , Humans , Quinolines , Steroids , SulfidesSubject(s)
Bile Duct Neoplasms/complications , Bile Duct Neoplasms/secondary , Carcinoma, Pancreatic Ductal/secondary , Common Bile Duct , Pancreatic Neoplasms/complications , Pancreatic Neoplasms/pathology , Bile Duct Neoplasms/surgery , Carcinoma, Pancreatic Ductal/complications , Carcinoma, Pancreatic Ductal/surgery , Female , Humans , Middle Aged , Pancreatic Neoplasms/surgery , Pancreatitis/diagnosis , Pancreatitis/etiologyABSTRACT
We report a 5-year-old girl with congenital hepatic fibrosis who presented with clubbing and cyanosis. Partial pressure of oxygen was 40 mmHg with oxy-gen saturation of 70% on room air, which improved to 128 mmHg and 92% on inhalation of 100% oxygen. Macroaggregated albumin scan showed 58% shunting to the brain, suggestive of severe hepatopulmonary syndrome. Echocardiogram and pulmonary angiogram ruled out pulmonary hypertension. Four weeks after living-related liver transplantation, she had normal blood gases and reduction in shunting to 7% on macroaggregated albumin scan.
Subject(s)
Hepatopulmonary Syndrome/complications , Liver Cirrhosis/congenital , Liver Transplantation , Living Donors , Brain/diagnostic imaging , Child, Preschool , Female , Follow-Up Studies , Hepatopulmonary Syndrome/diagnostic imaging , Hepatopulmonary Syndrome/surgery , Humans , Liver Cirrhosis/diagnostic imaging , Liver Cirrhosis/surgery , Lung/diagnostic imaging , Radionuclide Imaging , Technetium Tc 99m Aggregated Albumin , Treatment OutcomeSubject(s)
Abnormalities, Multiple , Ichthyosis , Lipid Metabolism, Inborn Errors , Female , Humans , Ichthyosis/diet therapy , Ichthyosis/pathology , Infant , Lipid Metabolism, Inborn Errors/diet therapy , Lipid Metabolism, Inborn Errors/pathology , Liver/pathology , Male , Neutrophils/pathology , Skin/pathology , Syndrome , Vacuoles/pathologyABSTRACT
A clinicopathological analysis of 18 cases of primary intracranial malignant lymphoma encountered in the period 1980 to 1994 is presented. The total SOL's in this period was 924, the incidence of malignant lymphoma working out to 2%. The patients age ranged from 14 to 72 years with maximum prevalence in the sixth and seventh decade. The male to female ratio was 2:1 and the patients presented with evidence of CNS deficit, change in mental status or raised ICI. 15 cases had a single site of involvement while 3 patients had multicentric lesions. As far as could be determined none of the cases had evidence of immunesuppression and test for HIV carried out in five cases was negative. All the tumors were subjected to light microscopy and the diagnosis was confirmed either by ultrastructural examination or immunohistochemistry. 13 tumors were large cell high grade lymphomas while the rest revealed smaller cells. Eleven patients received post operative radiotherapy and two were given post operative chemotherapy. The outcome of the patients was poor in most cases, fifteen out of eighteen died within two years.
Subject(s)
Central Nervous System Neoplasms/pathology , Lymphoma, Non-Hodgkin/pathology , Adolescent , Adult , Aged , Female , Humans , Male , Middle AgedABSTRACT
Two Indian male children with infantile-onset heavy proteinuria (with nephrotic syndrome in 1) had thickening of the glomerular basement membrane with splitting and basket-weave appearance of lamina densa on electron microscopic evaluation of kidney tissue (like Alport's syndrome), with normal light microscopic findings and negative immunofluorescence. The proteinuria was non-familial and was not associated with microhaematuria in patient 1; transient microhaematuria, perhaps associated with urinary tract infection, was noted in patient 2. There was no neurosensory deafness in the patients or their parents. The nephrotic syndrome remitted totally in one patient over a 7-month period. The proteinuria, as well as the renal disease, was non-progressive in the second patient over a 27-month period. The significance of these basement membrane abnormalities (classically described in Alport's syndrome) in early-onset nephrotic syndrome/heavy proteinuria that is non-familial and non-progressive needs to be evaluated.
Subject(s)
Basement Membrane/abnormalities , Kidney Glomerulus/abnormalities , Proteinuria/pathology , Basement Membrane/ultrastructure , Humans , Hypertrophy , Infant , Kidney/ultrastructure , Kidney Glomerulus/ultrastructure , Male , Nephritis, Hereditary/pathology , Nephrotic Syndrome/pathologyABSTRACT
Ten cases of cystosarcoma phyllodes are reported along with review of literature. The pathological features are outlined and principles of management are discussed.
Subject(s)
Breast Neoplasms/pathology , Phyllodes Tumor/pathology , Adolescent , Adult , Breast Neoplasms/surgery , Female , Humans , Middle Aged , Phyllodes Tumor/surgery , PrognosisABSTRACT
The term ossifying lipoma is used to describe a rare case of lipoma when its mature adipose tissue shows foci of chondrification and ossification. We are presenting here, a case report of a large sized ossifying lipoma in the anteromedial compartment of the left thigh of a 55 year old farmer.
