ABSTRACT
The authors consider that the application of Levamisol in the treatment of patients decreases the amount of complications if the degree of shock was not great. In greater degree of shock Levamisole failed to exert a favorable effect.
Subject(s)
Chemotaxis, Leukocyte/drug effects , Levamisole/therapeutic use , Shock, Traumatic/immunology , Adjuvants, Immunologic , Combined Modality Therapy , Humans , Leukocyte Count/drug effects , Respiratory Tract Infections/prevention & control , Shock, Traumatic/therapy , Time Factors , Wound Infection/prevention & control , Wounds and Injuries/complicationsSubject(s)
Leukocytes/physiology , Shock, Traumatic/physiopathology , Wounds and Injuries/physiopathology , Chemotaxis, Leukocyte , Hemodynamics , Humans , Inflammation/physiopathology , Monocytes/physiology , Neutrophils/physiology , Shock, Traumatic/complications , Time Factors , Wounds and Injuries/complicationsSubject(s)
Shock, Traumatic/immunology , Wounds and Injuries/immunology , Adjuvants, Immunologic/therapeutic use , B-Lymphocytes/immunology , Humans , Immunotherapy , Lymphocyte Activation , Neutrophils/immunology , Phagocytosis , Shock, Surgical , Shock, Traumatic/therapy , T-Lymphocytes/immunology , T-Lymphocytes, Regulatory/immunology , Wounds and Injuries/therapyABSTRACT
Inconsiderable hyponatremia and pronounced hypopotassemia were found to accompany the shock. In a mild course of the traumatic disease the concentration of natrium in blood plasma was restored within 3--6 days, potassium within 7--10 days after trauma, and in a grave course hypopotassemia retained for about 14 days. More continuous use of the infusion therapy including potassium and natrium was found to be expedient.
Subject(s)
Hypokalemia/etiology , Hyponatremia/etiology , Shock, Traumatic/blood , Humans , Potassium/blood , Sodium/blood , Time FactorsSubject(s)
Blood Cells/pathology , Shock, Traumatic/blood , Adult , Blood Cell Count , Female , Hemodynamics , Humans , Male , Middle Aged , Time Factors , Wounds and Injuries/bloodABSTRACT
The article analyzes changes in the protein metabolism of the organism of patients with associated trauma followed by shock. It was found that during shock and postshock period (as long as 14 days after trauma) of the traumatic disease hypoproteinemia was developing with the degree proportional to the severity of shock. To normalize protein metabolism it is necessary, in addition to a wide use of transfusions of blood and protein hydrolysates, to use protein mixtures (food concentrates) for oral feeding of critical patients in the complex of simultaneous measures directed to valuable correction of systemic and organic hemodynamics during this period.
Subject(s)
Blood Proteins/metabolism , Shock, Traumatic/blood , Wounds and Injuries/blood , Alanine Transaminase/blood , Aspartate Aminotransferases/blood , Hemodynamics , Humans , Time FactorsABSTRACT
The clinical course of an early (up to 14 days) postshock period of traumatic disease in 112 patients, treated for a combined trauma complicated with shock, has been studied. It has been established that within first 2 days after shock more than half of the patients develop increased coagulative activity of the blood, which rises still more in the following period. Progressive anemia, connected apparently with hemopoietic depression, is characteristic of the postshock period. In the second period (3--14 days after trauma) 60% of examined patients showed hypokalemia. A great percentage of inflammatory complications is likely to be due to the decrease of the defense--adaptative mechanisms, resulting from changes of the reactivity in the injured after shock.