ABSTRACT
Benign endometroid cystadenofibroma of the ovary is a rare tumour with few reported cases. The association of endometroid cystadenofibroma with endometrial cystic glandular hyperplasia has not been previously reported to authors' knowledge. We are reporting a 75-year-old postmenopausal woman who presented with a large abdominopelvic mass corresponding to 30 weeks size gravid uterus and postmenopausal bleeding. She has a well-oestrogenised vagina. Ultrasound pelvis revealed a large cystic mass extending from pelvis to epigastrium with no solid component and few incomplete septations and no internal echoes. MRI findings showed mainly cystic component with few moderately enhancing, fine, incomplete septa. Endometrial aspiration reported histopathology of cystic glandular hyperplasia without atypia. Serum oestrogen level reported to be high (210 pg/mL). Hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathology of the specimen revealed benign endometroid cystadenofibroma. She remained asymptomatic and disease free during her 6-month follow-up.
Subject(s)
Cystadenofibroma/diagnosis , Endometrial Hyperplasia/etiology , Endometrial Neoplasms/diagnosis , Ovarian Neoplasms/diagnosis , Postmenopause , Uterine Hemorrhage/etiology , Aged , Cystadenofibroma/complications , Cystadenofibroma/surgery , Diagnosis, Differential , Endometrial Neoplasms/complications , Endometrial Neoplasms/surgery , Female , Humans , Ovarian Neoplasms/complications , Ovarian Neoplasms/surgery , Treatment OutcomeABSTRACT
We report a 4-year-old boy presenting with a tense massive ascites and large hydrocele. History and physical examination were unremarkable. Routine laboratory studies were normal. Abdominal ultrasonography revealed massive ascites. Contrast CT was suggestive of a large cyst covering the entire peritoneal cavity. At laparotomy, a large cystic tumor was found extending into the scrotum through the left inguinal ring. Histopathologic examination diagnosed the tumor as a cystic lymphangiomatous hemartoma. Although abdominal lymphangiomas are seen in children, but presenting as massive ascites with hydrocele is very rare.
Subject(s)
Ascites/diagnosis , Hamartoma/pathology , Lymphangioma/pathology , Peritoneal Neoplasms/pathology , Testicular Hydrocele/diagnosis , Ascites/surgery , Child, Preschool , Diagnosis, Differential , Follow-Up Studies , Hamartoma/diagnosis , Hamartoma/surgery , Humans , Laparotomy , Lymphangioma/diagnosis , Lymphangioma/surgery , Male , Peritoneal Neoplasms/diagnosis , Peritoneal Neoplasms/surgery , Risk Assessment , Severity of Illness Index , Testicular Hydrocele/surgery , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, DopplerABSTRACT
Donovanosis is endemic in various parts of the world. Although donovanosis has been reported to co-exist with the human immunodeficiency virus (HIV) infection, to our knowledge there have been no reports of co-existent squamous cell carcinoma (SCC) in an HIV positive patient. In our case the patient did not respond to treatment for donovanosis and on biopsy we realized that the patient had coexistent SCC, which is hitherto unreported with granuloma inguinale.
Subject(s)
Carcinoma, Squamous Cell/complications , Granuloma Inguinale/complications , HIV Infections/complications , Penile Neoplasms/complications , Skin Neoplasms/complications , Amputation, Surgical , Anti-Bacterial Agents/therapeutic use , Anti-HIV Agents/therapeutic use , Antiretroviral Therapy, Highly Active , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/therapy , Cell Transformation, Neoplastic , Chemotherapy, Adjuvant , Combined Modality Therapy , Disease Progression , Doxycycline/therapeutic use , Granuloma Inguinale/drug therapy , Granuloma Inguinale/pathology , HIV Infections/diagnosis , HIV Infections/drug therapy , Humans , Male , Penile Neoplasms/pathology , Penile Neoplasms/therapy , Radiotherapy, Adjuvant , Skin Neoplasms/pathology , Skin Neoplasms/therapy , Skin Ulcer/etiology , Young AdultABSTRACT
Granulocytic sarcoma of the female genital tract is a rare occurrence. A case of a perimenopausal female is presented who reported with a history of menorrhagia with a lump in the abdomen. A diagnosis of fibroid uterus was made but laparotomy findings were suggestive of inoperable ovarian malignancy with metastases. Postoperatively the patient suddenly became very anemic. Hematological investigations and histopathological reports from ovaries, myometrium, endometrium and intraperitoneal deposits all revealed acute myeloid leukemia. The patient received two cycles of chemotherapy but later succumbed to her disease. Extrauterine causes of menorrhagia should be considered before instituting definitive treatment. Preoperative induction chemotherapy may be more successful in cases of granulocytic sarcoma who tend to have a poor prognosis.
Subject(s)
Genital Neoplasms, Female/diagnosis , Peritoneal Neoplasms/secondary , Sarcoma, Myeloid/diagnosis , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Fatal Outcome , Female , Genital Neoplasms, Female/therapy , Gynecologic Surgical Procedures , Humans , Peritoneal Neoplasms/therapy , Sarcoma, Myeloid/therapyABSTRACT
We report two sisters, ages 12 and 8 years, with the characteristic clinical and biochemical profile of congenital erythropoietic porphyria (CEP). The disease is inherited as an autosomal recessive. The elder sibling had squamous cell carcinoma arising from the stump of the amputated left arm with metastases to lymph nodes, adrenals, and bone. To our knowledge, this feature has not been described in the English language literature, making our patient the first documented report of CEP with squamous cell carcinoma.
