Momentary PERMA: An Adapted Measurement Tool for Studying Well-Being in Daily Life.

PERMA is a multidimensional framework that explains well-being through five hedonic and eudaimonic psychological elements-Positive emotions, Engagement, Relationships, Meaning, Accomplishment. Soon after the PERMA framework was proposed, PERMA-Profiler was introduced as a validated assessment tool for measuring these five elements of well-being from a global perspective. The current study aimed to shed further light onto the measurement of PERMA elements, extending it beyond global evaluations, to daily life assessments and the examination of individual differences in their dynamic characteristics. We introduce mPERMA (momentary PERMA), as an EMA-adapted version of the PERMA-Profiler measure, to assess well-being in daily life. Using data collected in an Ecological Momentary Assessment (EMA) study (N = 160), we first demonstrate the factor structure of mPERMA through a multilevel factor analysis and next examine within-person means and the dynamics of change (e.g., intra-individual variability) in the PERMA elements. Findings revealed that mPERMA displays convergent validity with two global measures of hedonic and eudaimonic well-being, namely Flourishing and Subjective Well-Being. Moreover, dynamical characteristics of the five elements of well-being measured over time, map onto their corresponding hedonic or eudaimonic global measures of well-being. Results of this paper present how dynamical features of well-being in daily life provide novel insights into predicting global well-being. Supplementary Information: The online version contains supplementary material available at 10.1007/s10902-023-00684-w.

Attention to emotional stimuli across adulthood and older age: A novel application of eye-tracking within the home.

Previous research has used stationary eye-tracking in the lab to examine age differences in attentional deployment, showing that older adults display gaze patterns toward positive stimuli. This positive gaze preference sometimes improves older adults' mood compared to their younger counterparts. However, the lab environment may lead to different emotion regulation behavior among older adults compared to what they do in their everyday life. We, therefore, present the first use of stationary eye-tracking within participants' homes to examine gaze patterns toward video clips of varying valence and to study age differences in emotional attention among younger, middle-aged, and older adults in a more naturalistic environment. We also compared these results to in-lab gaze preferences among the same participants. Older adults deployed attention more to positive stimuli in the lab but more to negative stimuli in the home. This increased attention to negative content in the home predicted higher self-reported arousal outcomes among middle-aged and older adults. Gaze preferences toward emotional stimuli may thus differ depending on the context, emphasizing the need to explore more naturalistic settings within emotion regulation and aging research. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Hydrocortisone may act through the angiotensin II receptor-2 level in patients with catecholamine-resistant septic shock.

BACKGROUND: This study aimed to compare the serum angiotensin II and its receptor levels (AT1, AT2) in septic patients with catecholamine-responsive or resistant. The effect of hydrocortisone treatment on angiotensin II levels in the catecholamine-resistant septic patients was evaluated. METHODS: This prospective observational study enrolled 40 patients diagnosed with septic shock based on sepsis-3 criteria. Patients were divided into two groups according to the noradrenalin infusion rate required to keep the mean arterial pressure above 65 mmHg: control group and hydrocortisone group (control group: below 0.5 µg/kg/min, hydrocortisone group: above 0.5 µg/kg/min). Serum angiotensin II, AT1, AT2 levels were measured at the time of diagnosis (A), one hour after hydrocortisone treatment (B), and three days later (C). RESULTS: In the catecholamine-resistant group, angiotensin II and AT1 levels were higher than the catecholamine-responder group in all periods. The sensitivity and specificity of AT-1 was observed to be high in all periods. AT2 levels decreased after hydrocortisone treatment in the catecholamine-resistant group and cut-off value was found 11%. CONCLUSIONS: It was concluded that angiotensin II and AT1 can be used as a biomarker of refractory septic shock and hydrocortisone may provide their blood pressure correcting effect by reducing AT2 level in these patients. AT2 can be a therapeutic target in the catecholamine-resistant septic shock patients.

Attention-focused emotion regulation in everyday life in adulthood and old age.

Although some lab studies suggest older adults rely more on attentional deployment to regulate their emotions, little is known about age differences in specific attention deployment tactic use and how they relate to mood regulation in everyday life. The current longitudinal experience sampling study considered several different attention deployment tactics, such as shifting or focusing attention to positive and negative elements either internally or externally (thoughts and feelings vs. external environment). Younger, middle-aged, and older adults (N = 236) responded to surveys about their affective experience five times a day for 5 days, five times over the course of a year; they reported on types of attention deployment they used, how they felt, and the nature of their current situation. We also considered the role of COVID-19. Positive attention deployment tactics were the most popular tactic for all age groups and were positively related to affective experience. However, younger adults used positive internal attention focus less than the other age groups, whereas older adults used all negative attention deployment tactics less than the other age groups (all ps < .05). After the onset of COVID, participants felt more negative and increased attention shift tactics, although this varied by age. Although older adults generally seem to shift and focus attention less frequently toward negative aspects than other age groups, life challenges (such as COVID-19) may modulate their use of positive attention deployment tactics. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Angiotensin II and angiotensin II receptor 2 levels can predict shock and mortality in septic patients.

BACKGROUND: The aim of this study was to evaluate the place of angiotensin II and its receptors in the prognosis of septic patients. METHODS: Patients with sepsis and septic shock were included in the study group. The control group consisted of patients who were followed up in the ICU and had no sepsis/septic shock. Plasma angiotensin II, angiotensin receptor-1 and 2 (AT-1, AT-2) levels were evaluated first and third days. RESULTS: Angiotensin II levels were significantly lower in the septic shock and non-survivor. AT-1 levels were lower in all septic patients on the first day compared to the control. While AT-1 levels on the third day decreased in the septic shock group, it increased in the sepsis group. AT-2 levels were significantly higher in sepsis, and lower in septic shock compared to controls on the first day. Angiotensin II (95%, 82%) and AT-2 levels (100%, 87%) were observed to have high sensitivity and specificity in demonstrating the presence of shock in septic patients. Angiotensin II and AT-1/AT-2 ratios were observed to have high sensitivity and low specificity in the development of mortality. CONCLUSIONS: In septic patients, angiotensin II, AT-2 and AT-1/AT-2 levels can predict the probability of shock development and mortality.