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Intern Med ; 57(3): 429-435, 2018 Feb 01.
Article in English | MEDLINE | ID: mdl-29093394

ABSTRACT

Mycobacterium bovis infection after intravesical Bacillus Calmette-Guérin (BCG) therapy is rare. A 65-year-old Japanese man with history of bladder cancer and intravesical BCG therapy, presented with low-grade fever. An aneurysm with perianeurysmal fluid was suspected and endovascular aortic repair was performed. After 160 days, he developed blood-streaked sputum and computed tomography images revealed that the perianeurysmal fluid area was increasing in size. A multiplex polymerase chain reaction using sputum identified M. bovis. Treatment with anti-tuberculosis drugs reduced the size of the perianeurysmal fluid area. After intravesical BCG therapy, the possibility of M. bovis infection should be considered, thus further investigations are required.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Aortic Aneurysm, Abdominal/etiology , Aortic Aneurysm, Abdominal/surgery , BCG Vaccine/therapeutic use , Mycobacterium Infections/drug therapy , Mycobacterium Infections/etiology , Tuberculosis, Cardiovascular/drug therapy , Vascular Surgical Procedures/adverse effects , Administration, Intravesical , Aged , Aortic Aneurysm, Abdominal/microbiology , Asian People , Humans , Male , Tomography, X-Ray Computed , Treatment Outcome , Tretoquinol , Tuberculosis, Cardiovascular/diagnosis , Tuberculosis, Cardiovascular/microbiology , Tuberculosis, Cardiovascular/surgery
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